TY - JOUR
T1 - Strategy to mask the bitter taste of momordica charantia extract using alginate–gelatin beads
AU - Sutriyo,
AU - Iswandana, Raditya
AU - Fauzi, Fauzana
N1 - Publisher Copyright:
© 2018 The Authors.
PY - 2018
Y1 - 2018
N2 - Objective: This study is aimed to develop a strategy to mask the bitter taste of Momordica charantia Linn. extract using alginate–gelatin beads. Methods: Beads of bitter melon fruit extract (M. charantia Linn) were prepared using an ionic gelation method in which cross-linking occurs between sodium alginate and calcium chloride that serves to mask the bitter taste. Beads were prepared using sodium alginate (1.5% w/v) with various concentrations of bitter melon fruit extract (1:2, 1:1, and 1:0.5), gelatin (2% w/v), and CaCl2 3%. The obtained beads were then characterized both physically and functionally, and their morphology, process efficiency, particle distribution, swelling index, and water content were recorded. Results: Formula 1 beads, with a 1:2 ratio of extract: alginate, displayed a near-round shape with a diameter of 600–1 200 μm, a swelling index of 113.21%, and a moisture content of 15.34%. In addition, these beads were able to significantly cover the bitter taste (p<0.05). Conclusion: Formula 1 beads with a 1:2 ratio of extract: alginate can effectively mask the bitter taste of M. charantia Linn.
AB - Objective: This study is aimed to develop a strategy to mask the bitter taste of Momordica charantia Linn. extract using alginate–gelatin beads. Methods: Beads of bitter melon fruit extract (M. charantia Linn) were prepared using an ionic gelation method in which cross-linking occurs between sodium alginate and calcium chloride that serves to mask the bitter taste. Beads were prepared using sodium alginate (1.5% w/v) with various concentrations of bitter melon fruit extract (1:2, 1:1, and 1:0.5), gelatin (2% w/v), and CaCl2 3%. The obtained beads were then characterized both physically and functionally, and their morphology, process efficiency, particle distribution, swelling index, and water content were recorded. Results: Formula 1 beads, with a 1:2 ratio of extract: alginate, displayed a near-round shape with a diameter of 600–1 200 μm, a swelling index of 113.21%, and a moisture content of 15.34%. In addition, these beads were able to significantly cover the bitter taste (p<0.05). Conclusion: Formula 1 beads with a 1:2 ratio of extract: alginate can effectively mask the bitter taste of M. charantia Linn.
KW - Alginate
KW - Beads
KW - Bitter melon extract (momordica charantia Linn.)
KW - Bitter taste masking
KW - Gelatin
UR - http://www.scopus.com/inward/record.url?scp=85059800491&partnerID=8YFLogxK
U2 - 10.22159/ijap.2018.v10s1.84
DO - 10.22159/ijap.2018.v10s1.84
M3 - Article
AN - SCOPUS:85059800491
SN - 0975-7058
VL - 10
SP - 381
EP - 383
JO - International Journal of Applied Pharmaceutics
JF - International Journal of Applied Pharmaceutics
IS - Special Issue 1
ER -