Strategy to mask the bitter taste of momordica charantia extract using alginate–gelatin beads

Sutriyo, Raditya Iswandana, Fauzana Fauzi

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Objective: This study is aimed to develop a strategy to mask the bitter taste of Momordica charantia Linn. extract using alginate–gelatin beads. Methods: Beads of bitter melon fruit extract (M. charantia Linn) were prepared using an ionic gelation method in which cross-linking occurs between sodium alginate and calcium chloride that serves to mask the bitter taste. Beads were prepared using sodium alginate (1.5% w/v) with various concentrations of bitter melon fruit extract (1:2, 1:1, and 1:0.5), gelatin (2% w/v), and CaCl2 3%. The obtained beads were then characterized both physically and functionally, and their morphology, process efficiency, particle distribution, swelling index, and water content were recorded. Results: Formula 1 beads, with a 1:2 ratio of extract: alginate, displayed a near-round shape with a diameter of 600–1 200 μm, a swelling index of 113.21%, and a moisture content of 15.34%. In addition, these beads were able to significantly cover the bitter taste (p<0.05). Conclusion: Formula 1 beads with a 1:2 ratio of extract: alginate can effectively mask the bitter taste of M. charantia Linn.

Original languageEnglish
Pages (from-to)381-383
Number of pages3
JournalInternational Journal of Applied Pharmaceutics
Volume10
Issue numberSpecial Issue 1
DOIs
Publication statusPublished - 2018

Keywords

  • Alginate
  • Beads
  • Bitter melon extract (momordica charantia Linn.)
  • Bitter taste masking
  • Gelatin

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