Strategies of tuberculosis-HIV vaccines design using immunoinformatic approach

Ani Fatonah, I. Satrio Wicaksono, Usman Sumo Friend Tambunan

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Tuberculosis is amongst the highest cause death worldwide. According to WHO, an estimated of more than a million people fell ill with Tuberculosis (TB) in 2016. The resistances of the M. tuberculosis (MTb) bacteria make drugs, not that useful in battle with TB. Vaccination is a better choice to avoid the worst cases of TB. The resistance possessed by MTb bacteria with some of the drugs reported creates its challenge to reduce the high rate of TB related death. One of the concerns is the high mortality rate due to TB associated with HIV. However, there’s still no effective vaccine for Tuberculosis-Human Immunodeficiency Virus (TB-HIV). Vaccines for Tuberculosis-HIV even on the way of progress to get the demanding the mutation of the bacteria and challenging scientists to get the right vaccines for this disease. Immunoinformatic is one of the approaches that can speed up the making of the vaccine.

Original languageEnglish
Pages (from-to)110-116
Number of pages7
JournalOnLine Journal of Biological Sciences
Volume19
Issue number2
DOIs
Publication statusPublished - 1 Jan 2019

Keywords

  • Human immunodeficiency virus
  • M. tuberculosis
  • Tuberculosis
  • Tuberculosis-human immunodeficiency virus
  • Vaccine

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