Along with the development of hospitals and information technology, the Soewondo RAA Hospital Information System (SIRS) felt unable to meet the information needs. These limitations make the management of SIRS plans to replace their SIRS. In order for successful implementation of new SIRS, change management strategy needs to be done right at the hospital. This study aims to formulate strategies for implementing change management in the RAA Soewondo SIRS. The study was conducted using data collection through questionnaires, interviews, and observation. Action changes obtained with SWOT analysis and then grouped into a management method for making the change management strategy. Change management method that had been used is Anderson and Anderson Nine Phase Model. The study shows that the staffâ€™s resistance is relatively small. Action changes according that related to change management is leadership support for implementation of changes to SIRS, making equality vision and mission to all parts of the hospital about the change of SIRS, designing state of the desired changes with respect to the division that is affected by changes in SIRS, do the replacement with parallel cutover method , presents awards to employees who make this program succeed, and create new policies to estabilish policies that are already running to be permanent. The final results shows: in general, the employees agreed to change the current SIRS.