TY - JOUR
T1 - Stool antigen examination as a diagnostic tool for dyspeptic patient caused by helicobacter pylori infection
T2 - A case-based literature review
AU - Lestari, Haifa Mayang
AU - Gustinanda, Jatmiko
AU - Tejaputri, Nadzila Anindya
AU - Tumpu, Nur Afiahuddin
AU - Radifan, Taris
AU - Louisa, Melva
N1 - Funding Information:
We thanked the Directorate of Research and Community Engagement Universitas Indonesia, for the support in International Publication Grant.
Publisher Copyright:
© 2021 Haifa Mayang Lestari, Jatmiko Gustinanda, Nadzila Anindya Tejaputri, Nur Afiahuddin Tumpu, Taris Radifan, Melva Louisa.
PY - 2021/1/10
Y1 - 2021/1/10
N2 - Today, the gold standard for diagnosing Helicobacter pylori infection is by urea breath test (UBT). However, UBT tests are not widely available in several remote areas in Indonesia. Stool antigen test (SAT) is an alternative diagnostic test for H. pylori infection. However, it is unclear whether the performance of SAT to diagnose H. pylori infection can be comparable with UBT accuracy. This report was aimed to determine the accuracy of SAT to diagnose H. pylori infection as an alternative to UBT. Our case-based literature review indicates that SAT has high sensitivity (79–96.4%); therefore, SAT can help doctors in ruling out H. pylori infection. SAT also demonstrates remarkable specificity of stool antigen examination (98.6–100%), suggesting that SAT can help doctors in ruling in H. pylori infection.
AB - Today, the gold standard for diagnosing Helicobacter pylori infection is by urea breath test (UBT). However, UBT tests are not widely available in several remote areas in Indonesia. Stool antigen test (SAT) is an alternative diagnostic test for H. pylori infection. However, it is unclear whether the performance of SAT to diagnose H. pylori infection can be comparable with UBT accuracy. This report was aimed to determine the accuracy of SAT to diagnose H. pylori infection as an alternative to UBT. Our case-based literature review indicates that SAT has high sensitivity (79–96.4%); therefore, SAT can help doctors in ruling out H. pylori infection. SAT also demonstrates remarkable specificity of stool antigen examination (98.6–100%), suggesting that SAT can help doctors in ruling in H. pylori infection.
KW - Helicobacter pylori
KW - Stool antigen test
KW - Urea breath test
UR - http://www.scopus.com/inward/record.url?scp=85116395737&partnerID=8YFLogxK
U2 - 10.3889/oamjms.2021.5568
DO - 10.3889/oamjms.2021.5568
M3 - Review article
AN - SCOPUS:85116395737
SN - 1857-5749
VL - 9
SP - 305
EP - 309
JO - Open Access Macedonian Journal of Medical Sciences
JF - Open Access Macedonian Journal of Medical Sciences
IS - F
ER -