TY - JOUR
T1 - Silicasupported copper(II) oxide for the synthesis of curcumin derivatives containing pyrazole and isoxazole scaffolds
AU - Cahyana, Antonius Herry
AU - Ardiansah, Bayu
AU - Ibrahim, Wahyu Hidayat
N1 - Publisher Copyright:
© RASĀYAN. All rights reserved.
PY - 2019/4/1
Y1 - 2019/4/1
N2 - Preparation of CuO/SiO 2 catalyst has been done via sol-gel method using copper nitrate solution and TEOS as precursors. Several instruments such as FT-IR, SEM, EDAX, XRD and particle sizer were employed to characterize the obtained material. Then, CuO/SiO 2 catalyst was successfullyusedin the synthesis of three curcumin derivatives, 4,4'-((1E,1‘E)-(1H-pyrazole-3,5-diyl)bis(ethene-2,1-diyl))bis(2-methoxyphenol) (Compound 1), 4,4'-((1E,1‘E)-(1- phenyl-1H-pyrazole-3,5-diyl)bis(ethene-2,1-diyl))bis(2-methoxyphenol) (Compound 2) and 4,4'-((1E,1‘E)- (isoxazole-3,5-diylbis(ethene-2,1-diyl))bis(2-methoxyphenol) (Compound 3) with good yields.
AB - Preparation of CuO/SiO 2 catalyst has been done via sol-gel method using copper nitrate solution and TEOS as precursors. Several instruments such as FT-IR, SEM, EDAX, XRD and particle sizer were employed to characterize the obtained material. Then, CuO/SiO 2 catalyst was successfullyusedin the synthesis of three curcumin derivatives, 4,4'-((1E,1‘E)-(1H-pyrazole-3,5-diyl)bis(ethene-2,1-diyl))bis(2-methoxyphenol) (Compound 1), 4,4'-((1E,1‘E)-(1- phenyl-1H-pyrazole-3,5-diyl)bis(ethene-2,1-diyl))bis(2-methoxyphenol) (Compound 2) and 4,4'-((1E,1‘E)- (isoxazole-3,5-diylbis(ethene-2,1-diyl))bis(2-methoxyphenol) (Compound 3) with good yields.
KW - Curcumin
KW - Heterogeneous catalyst
KW - Isoxazole
KW - Pyrazole
UR - http://www.scopus.com/inward/record.url?scp=85064650906&partnerID=8YFLogxK
U2 - 10.31788/RJC.2019.1225011
DO - 10.31788/RJC.2019.1225011
M3 - Article
AN - SCOPUS:85064650906
SN - 0974-1496
VL - 12
SP - 471
EP - 477
JO - Rasayan Journal of Chemistry
JF - Rasayan Journal of Chemistry
IS - 2
ER -