Serum lipids in Norplant® implants users: A cross-sectional study

Biran Affandi; Suharti K Suherman; Djajalelana; Joedo Prihartono; F. Lubis; R. S. Samil

doi:10.1016/0010-7824(87)90091-6

Serum lipids in Norplant® implants users: A cross-sectional study

Biran Affandi, Suharti K Suherman, Djajalelana, Joedo Prihartono, F. Lubis, R. S. Samil

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17 Citations (Scopus)

Abstract

One of the methods to establish the safety and risk profile of hormonal contraceptives is employing a study on their metabolic effects. In order to evaluate the effect of Norplant® implants on serum lipids, a cross-sectional study was undertaken at Klinik Raden Saleh, Jakarta. The subjects recruited were divided into 8 groups depending on the length of Norplant® use, i.e. before insertion, 6 months, 12 months, 24 months, 36 months, 48 months, 60 months and one week after the removal of Norplant®. Blood samples were collected from the subjects after an overnight fast. The parameters studied were triglycerides, total cholesterol, HDL-cholesterol and LDL-cholesterol. There were no significant differences between the groups regarding the triglycerides and HDL-cholesterol (p > 0.05). There were significant differences between the groups regarding the total cholesterol and LDL-cholesterol (p < 0.01).

Original language	English
Pages (from-to)	429-434
Number of pages	6
Journal	Contraception
Volume	36
Issue number	4
DOIs	https://doi.org/10.1016/0010-7824(87)90091-6
Publication status	Published - 1 Jan 1987

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Affandi, B., Suherman, S. K., Djajalelana, Prihartono, J., Lubis, F., & Samil, R. S. (1987). Serum lipids in Norplant® implants users: A cross-sectional study. Contraception, 36(4), 429-434. https://doi.org/10.1016/0010-7824(87)90091-6

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abstract = "One of the methods to establish the safety and risk profile of hormonal contraceptives is employing a study on their metabolic effects. In order to evaluate the effect of Norplant{\textregistered} implants on serum lipids, a cross-sectional study was undertaken at Klinik Raden Saleh, Jakarta. The subjects recruited were divided into 8 groups depending on the length of Norplant{\textregistered} use, i.e. before insertion, 6 months, 12 months, 24 months, 36 months, 48 months, 60 months and one week after the removal of Norplant{\textregistered}. Blood samples were collected from the subjects after an overnight fast. The parameters studied were triglycerides, total cholesterol, HDL-cholesterol and LDL-cholesterol. There were no significant differences between the groups regarding the triglycerides and HDL-cholesterol (p > 0.05). There were significant differences between the groups regarding the total cholesterol and LDL-cholesterol (p < 0.01).",

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AU - Samil, R. S.

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