Selection of discrimination marker from various propolis for mapping and identify anti Candida albicans activity

Alfiani Guntari Mahadewi; Daisy Christina; Heri Hermansyah; Anondho Wijanarko; Siti Farida; Robiatul Adawiyah; Etin Rohmatin; Muhamad Sahlan

doi:10.1063/1.5023939

Selection of discrimination marker from various propolis for mapping and identify anti Candida albicans activity

Alfiani Guntari Mahadewi, Daisy Christina, Heri Hermansyah, Anondho Wijanarko, Siti Farida, Robiatul Adawiyah, Etin Rohmatin, Muhamad Sahlan

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

8 Citations (Scopus)

Abstract

The increase in fungal resistance against antifungal drugs available in the market will reduce the effectiveness of treatment for Candidiasis. Propolis contains various compounds with antifungal properties Candida albicans, but the content of each type is very diverse. The sample used was Sulawesi propolis type smooth (taken from inside the nest), rough (taken from outside the hive) and mix (a combination of both). Anti-C. albicans molecule marker is a marker compound for selecting propolis with the ability to overcome Candidiasis. The initial step was to test the levels of flavonoids and phenolic by using UV-Vis spectrometry method. It was founded that each sample was not always superior to any substance, so propolis cannot be directly selected. In Phenolic content, mix propolis has the highest value than other 5.109%. In Flavonoid content, propolis smooth has the highest value than other, 16.38%. Furthermore, propolis selected by antifungal activity test with good diffusion method at the concentration propolis 5% either 7%, the inhibitory diameter zone propolis smooth and rough has same value 10 mm. Propolis mix has an advantage while propolis smooth and rough have the same capability range 12 mm and 13 mm. In this study, the phenolic content plays a major role in antifungal cases.

Original language	English
Title of host publication	2nd Biomedical Engineering�s Recent Progress in Biomaterials, Drugs Development, and Medical Devices
Subtitle of host publication	Proceedings of the International Symposium of Biomedical Engineering, ISBE 2017
Editors	Radon Dhelika, Yudan Whulanza, Ghiska Ramahdita, Praswasti P.D.K. Wulan
Publisher	American Institute of Physics Inc.
ISBN (Electronic)	9780735416253
DOIs	https://doi.org/10.1063/1.5023939
Publication status	Published - 13 Feb 2018
Event	2nd Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2017 - Bali, Indonesia Duration: 25 Jul 2017 → 26 Jul 2017

Publication series

Name	AIP Conference Proceedings
Volume	1933
ISSN (Print)	0094-243X
ISSN (Electronic)	1551-7616

Conference

Conference	2nd Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2017
Country/Territory	Indonesia
City	Bali
Period	25/07/17 → 26/07/17

Keywords

Candida albicans
Diffuse well
Molecular Marker

Access to Document

10.1063/1.5023939

Cite this

Mahadewi, A. G., Christina, D., Hermansyah, H., Wijanarko, A., Farida, S., Adawiyah, R., Rohmatin, E., & Sahlan, M. (2018). Selection of discrimination marker from various propolis for mapping and identify anti Candida albicans activity. In R. Dhelika, Y. Whulanza, G. Ramahdita, & P. P. D. K. Wulan (Eds.), 2nd Biomedical Engineering�s Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the International Symposium of Biomedical Engineering, ISBE 2017 [020005] (AIP Conference Proceedings; Vol. 1933). American Institute of Physics Inc.. https://doi.org/10.1063/1.5023939

Mahadewi, Alfiani Guntari ; Christina, Daisy ; Hermansyah, Heri et al. / Selection of discrimination marker from various propolis for mapping and identify anti Candida albicans activity. 2nd Biomedical Engineering�s Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the International Symposium of Biomedical Engineering, ISBE 2017. editor / Radon Dhelika ; Yudan Whulanza ; Ghiska Ramahdita ; Praswasti P.D.K. Wulan. American Institute of Physics Inc., 2018. (AIP Conference Proceedings).

@inproceedings{8ad88cc104f343cda817332833dfc8ac,

title = "Selection of discrimination marker from various propolis for mapping and identify anti Candida albicans activity",

abstract = "The increase in fungal resistance against antifungal drugs available in the market will reduce the effectiveness of treatment for Candidiasis. Propolis contains various compounds with antifungal properties Candida albicans, but the content of each type is very diverse. The sample used was Sulawesi propolis type smooth (taken from inside the nest), rough (taken from outside the hive) and mix (a combination of both). Anti-C. albicans molecule marker is a marker compound for selecting propolis with the ability to overcome Candidiasis. The initial step was to test the levels of flavonoids and phenolic by using UV-Vis spectrometry method. It was founded that each sample was not always superior to any substance, so propolis cannot be directly selected. In Phenolic content, mix propolis has the highest value than other 5.109%. In Flavonoid content, propolis smooth has the highest value than other, 16.38%. Furthermore, propolis selected by antifungal activity test with good diffusion method at the concentration propolis 5% either 7%, the inhibitory diameter zone propolis smooth and rough has same value 10 mm. Propolis mix has an advantage while propolis smooth and rough have the same capability range 12 mm and 13 mm. In this study, the phenolic content plays a major role in antifungal cases.",

keywords = "Candida albicans, Diffuse well, Molecular Marker",

author = "Mahadewi, {Alfiani Guntari} and Daisy Christina and Heri Hermansyah and Anondho Wijanarko and Siti Farida and Robiatul Adawiyah and Etin Rohmatin and Muhamad Sahlan",

note = "Publisher Copyright: {\textcopyright} 2018 Author(s). Published by AIP Publishing.; 2nd Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2017 ; Conference date: 25-07-2017 Through 26-07-2017",

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Mahadewi, AG, Christina, D, Hermansyah, H, Wijanarko, A, Farida, S , Adawiyah, R, Rohmatin, E & Sahlan, M 2018, Selection of discrimination marker from various propolis for mapping and identify anti Candida albicans activity. in R Dhelika, Y Whulanza, G Ramahdita & PPDK Wulan (eds), 2nd Biomedical Engineering�s Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the International Symposium of Biomedical Engineering, ISBE 2017., 020005, AIP Conference Proceedings, vol. 1933, American Institute of Physics Inc., 2nd Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2017, Bali, Indonesia, 25/07/17. https://doi.org/10.1063/1.5023939

Selection of discrimination marker from various propolis for mapping and identify anti Candida albicans activity. / Mahadewi, Alfiani Guntari; Christina, Daisy; Hermansyah, Heri et al.

2nd Biomedical Engineering�s Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the International Symposium of Biomedical Engineering, ISBE 2017. ed. / Radon Dhelika; Yudan Whulanza; Ghiska Ramahdita; Praswasti P.D.K. Wulan. American Institute of Physics Inc., 2018. 020005 (AIP Conference Proceedings; Vol. 1933).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Selection of discrimination marker from various propolis for mapping and identify anti Candida albicans activity

AU - Mahadewi, Alfiani Guntari

AU - Christina, Daisy

AU - Hermansyah, Heri

AU - Wijanarko, Anondho

AU - Farida, Siti

AU - Adawiyah, Robiatul

AU - Rohmatin, Etin

AU - Sahlan, Muhamad

PY - 2018/2/13

Y1 - 2018/2/13

N2 - The increase in fungal resistance against antifungal drugs available in the market will reduce the effectiveness of treatment for Candidiasis. Propolis contains various compounds with antifungal properties Candida albicans, but the content of each type is very diverse. The sample used was Sulawesi propolis type smooth (taken from inside the nest), rough (taken from outside the hive) and mix (a combination of both). Anti-C. albicans molecule marker is a marker compound for selecting propolis with the ability to overcome Candidiasis. The initial step was to test the levels of flavonoids and phenolic by using UV-Vis spectrometry method. It was founded that each sample was not always superior to any substance, so propolis cannot be directly selected. In Phenolic content, mix propolis has the highest value than other 5.109%. In Flavonoid content, propolis smooth has the highest value than other, 16.38%. Furthermore, propolis selected by antifungal activity test with good diffusion method at the concentration propolis 5% either 7%, the inhibitory diameter zone propolis smooth and rough has same value 10 mm. Propolis mix has an advantage while propolis smooth and rough have the same capability range 12 mm and 13 mm. In this study, the phenolic content plays a major role in antifungal cases.

AB - The increase in fungal resistance against antifungal drugs available in the market will reduce the effectiveness of treatment for Candidiasis. Propolis contains various compounds with antifungal properties Candida albicans, but the content of each type is very diverse. The sample used was Sulawesi propolis type smooth (taken from inside the nest), rough (taken from outside the hive) and mix (a combination of both). Anti-C. albicans molecule marker is a marker compound for selecting propolis with the ability to overcome Candidiasis. The initial step was to test the levels of flavonoids and phenolic by using UV-Vis spectrometry method. It was founded that each sample was not always superior to any substance, so propolis cannot be directly selected. In Phenolic content, mix propolis has the highest value than other 5.109%. In Flavonoid content, propolis smooth has the highest value than other, 16.38%. Furthermore, propolis selected by antifungal activity test with good diffusion method at the concentration propolis 5% either 7%, the inhibitory diameter zone propolis smooth and rough has same value 10 mm. Propolis mix has an advantage while propolis smooth and rough have the same capability range 12 mm and 13 mm. In this study, the phenolic content plays a major role in antifungal cases.

KW - Candida albicans

KW - Diffuse well

KW - Molecular Marker

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BT - 2nd Biomedical Engineering�s Recent Progress in Biomaterials, Drugs Development, and Medical Devices

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Mahadewi AG, Christina D, Hermansyah H, Wijanarko A, Farida S , Adawiyah R et al. Selection of discrimination marker from various propolis for mapping and identify anti Candida albicans activity. In Dhelika R, Whulanza Y, Ramahdita G, Wulan PPDK, editors, 2nd Biomedical Engineering�s Recent Progress in Biomaterials, Drugs Development, and Medical Devices: Proceedings of the International Symposium of Biomedical Engineering, ISBE 2017. American Institute of Physics Inc. 2018. 020005. (AIP Conference Proceedings). doi: 10.1063/1.5023939

Selection of discrimination marker from various propolis for mapping and identify anti Candida albicans activity

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