Secondary metabolite isolated from Indonesian white turmeric (Curcuma zedoaria) rhizomes and its potential as antibacterial agent

White turmeric (Curcuma zedoaria) is widely grown in Southeast and South Asia including Indonesia and as a spice and vegetable. It is commonly used traditionally for the treatment of various diseases. The objective research is to isolate alkaloids and terpenoids from C. zedoaria rhizomes from Bogor, West Java, Indonesia, and reviewed by literature studies its potency as an antibacterial agent. C. zedoaria rhizomes were extracted by maceration under methanol then followed by increasing solvent polarity. the n-Hexane fraction was further purified by using chromatography techniques to afford a simple fraction. The simple fraction then was analyzed by LCMS/MS and the result showed that it was as a mixture content of alkaloids and terpenoids types, such as trichostachine, piperine, curzerenone, and curcumenol. The literature studies revealed that C. zedoaria rhizomes extract could be developed as an antibacterial agent.