Scoring System Development and Added Value of Albuminuria to Estimate Carotid Intima-media Thickness (CIMT) in Type 2 Diabetes Mellitus Patients

Indra Wijaya, Em Yunir, Dharmeizar Dharmeizar, Ika Prasetya Wijaya, Siti Setiati

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

AIM: to develop a scoring system and measure the diagnostic added value of albuminuria to estimate CIMT.

METHODS: cross-sectional study was done in Endocrine Outpatient Clinic Cipto Mangunkusumo Hospital between March-May 2012 in T2DM patients without history of cerebrocardiovascular event, CKD stage ≥ III, and smoking. Bivariate analysis and multivariate (logistic regression) analysis was done, followed by developing the scoring system.

RESULTS: from 71 subjects, there were 67.6% with increased CIMT and 73.3% with albuminuria. From 48 subjects with increased CIMT, 87.5% had albuminuria. Albuminuria measurement had high sensitivity (87.5%). Adding albuminuria measurement will increase the AUC as 2.3%. Estimation score for duration of DM, hypertension, dyslipidemia were as follows 1, 2, 1 respectively. Probability score of increased CIMT for score <2, 2, and >2 was as follows 15%, 57%, and 90%.

CONCLUSION: albuminuria measurement increase the diagnostic value of CIMT. Scoring system can be used as a screening tool to estimate the increased of CIMT in type 2 DM patients without history of cerebrocardiovascular event, CKD stage ≥ III, and smoking.

Original languageEnglish
Pages (from-to)269-274
Number of pages6
JournalActa medica Indonesiana
Volume48
Issue number4
Publication statusPublished - 1 Oct 2016

Keywords

  • albuminuria
  • carotid intima-media thickness
  • type 2 diabetes mellitus

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