Scattering of two spin-1\2 particles is formulated in a three-dimensional approach based on a simple three-dimensional momentum-spin basis. Both cases of identical and nonidentical particles are considered. The azimuthal behaviour of the potential and of the T-matrix elements leads to a set of integral equations for the T-matrix elements in two variables, i.e. the momentum magnitude and the scattering angle. Observables can be directly calculated from these T-matrix elements. Some symmetry relations for the T-matrix elements reduce the number of equations to be solved.