TY - JOUR
T1 - Salivary secretory immunoglobulin a level of children with acute lymphoblastic leukemia in maintenance phase
AU - Rani, Danar Pradipta
AU - Budiardjo, Sarworini B.
AU - Soetopo, Margaretha Suharsini
N1 - Publisher Copyright:
© 2018 The Authors.
PY - 2018/3
Y1 - 2018/3
N2 - Objective: The objective of this research is to investigate the differences in salivary secretory immunoglobulin A (sIgA) levels between children with gingivitis who have acute lymphoblastic leukemia (ALL) and are in the maintenance phase of chemotherapy and the levels in healthy children with gingivitis. Methods: This study used cross-sectional and laboratory observation methods with 19 ALL children and 19 healthy children who all had mild gingivitis. Two mL of saliva were collected and stored at −200°C. Then, salivary sIgA levels were measured using the ELISA method. Results: The results indicate an insignificant difference (p>0.05) in salivary sIgA levels between the ALL children in the maintenance phase with the level of 21.38 (7.23–107.26) and 37.26 (11.24–135.63) for the healthy children. Conclusion: There is no significant difference in salivary sIgA levels between the ALL children in the maintenance phase and the healthy children.
AB - Objective: The objective of this research is to investigate the differences in salivary secretory immunoglobulin A (sIgA) levels between children with gingivitis who have acute lymphoblastic leukemia (ALL) and are in the maintenance phase of chemotherapy and the levels in healthy children with gingivitis. Methods: This study used cross-sectional and laboratory observation methods with 19 ALL children and 19 healthy children who all had mild gingivitis. Two mL of saliva were collected and stored at −200°C. Then, salivary sIgA levels were measured using the ELISA method. Results: The results indicate an insignificant difference (p>0.05) in salivary sIgA levels between the ALL children in the maintenance phase with the level of 21.38 (7.23–107.26) and 37.26 (11.24–135.63) for the healthy children. Conclusion: There is no significant difference in salivary sIgA levels between the ALL children in the maintenance phase and the healthy children.
KW - Acute lymphoblastic leukemia
KW - Gingivitis
KW - Maintenance phase
KW - Salivary secretory immunoglobulin A
UR - http://www.scopus.com/inward/record.url?scp=85042934623&partnerID=8YFLogxK
U2 - 10.22159/ajpcr.2018.v11i3.23261
DO - 10.22159/ajpcr.2018.v11i3.23261
M3 - Article
AN - SCOPUS:85042934623
SN - 0974-2441
VL - 11
SP - 50
EP - 52
JO - Asian Journal of Pharmaceutical and Clinical Research
JF - Asian Journal of Pharmaceutical and Clinical Research
IS - 3
ER -