Salivary secretory immunoglobulin a level of children with acute lymphoblastic leukemia in maintenance phase

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Abstract

Objective: The objective of this research is to investigate the differences in salivary secretory immunoglobulin A (sIgA) levels between children with gingivitis who have acute lymphoblastic leukemia (ALL) and are in the maintenance phase of chemotherapy and the levels in healthy children with gingivitis. Methods: This study used cross-sectional and laboratory observation methods with 19 ALL children and 19 healthy children who all had mild gingivitis. Two mL of saliva were collected and stored at −200°C. Then, salivary sIgA levels were measured using the ELISA method. Results: The results indicate an insignificant difference (p>0.05) in salivary sIgA levels between the ALL children in the maintenance phase with the level of 21.38 (7.23–107.26) and 37.26 (11.24–135.63) for the healthy children. Conclusion: There is no significant difference in salivary sIgA levels between the ALL children in the maintenance phase and the healthy children.

Original languageEnglish
Pages (from-to)50-52
Number of pages3
JournalAsian Journal of Pharmaceutical and Clinical Research
Volume11
Issue number3
DOIs
Publication statusPublished - 1 Mar 2018

Keywords

  • Acute lymphoblastic leukemia
  • Gingivitis
  • Maintenance phase
  • Salivary secretory immunoglobulin A

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