TY - JOUR
T1 - Salivary bone-specific alkaline phosphatase as predictor of puberty phase
AU - Wijaya, Harryanto
AU - Kusdhany, Lindawati S.
AU - Redjeki, Sri
AU - Soegiharto, Benny M.
N1 - Publisher Copyright:
© 2019, Journal of International Dental and Medical Research.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - The identification of the puberty phase is crucial, as it enhances the efficiency and effectiveness of malocclusion treatment. The observation or evaluation of bone morphology developments and changes through radiographs, known as the skeletal maturation method, is the most valid puberty phase indicator. Since this method requires radiographic exposure, a new, non-invasive prediction method for the puberty phase is needed. This study aimed to analyze the potential of the level of salivary bone-specific alkaline phosphatase (BALP), chronological age, and Body Mass Index (BMI) percentile as predictors of the puberty phase. The cross-sectional study included 136 subjects categorized into three phases of puberty based on Bacceti's Cervical Vertebrae Maturation System. Salivary BALP level was determined using a commercial enzyme-linked immunosorbent assay kit. Multinomial logistic regression analysis produced a predictive model with a correct classification rate of 78% in the pre-peak phase, 57.7% in the peak phase, and 81.4% in the post-peak phase. The puberty phase, especially at pre and post-peak, can be predicted with salivary BALP level, chronological age, and BMI percentile.
AB - The identification of the puberty phase is crucial, as it enhances the efficiency and effectiveness of malocclusion treatment. The observation or evaluation of bone morphology developments and changes through radiographs, known as the skeletal maturation method, is the most valid puberty phase indicator. Since this method requires radiographic exposure, a new, non-invasive prediction method for the puberty phase is needed. This study aimed to analyze the potential of the level of salivary bone-specific alkaline phosphatase (BALP), chronological age, and Body Mass Index (BMI) percentile as predictors of the puberty phase. The cross-sectional study included 136 subjects categorized into three phases of puberty based on Bacceti's Cervical Vertebrae Maturation System. Salivary BALP level was determined using a commercial enzyme-linked immunosorbent assay kit. Multinomial logistic regression analysis produced a predictive model with a correct classification rate of 78% in the pre-peak phase, 57.7% in the peak phase, and 81.4% in the post-peak phase. The puberty phase, especially at pre and post-peak, can be predicted with salivary BALP level, chronological age, and BMI percentile.
KW - Body Mass Index
KW - Cervical Vertebrae Maturation System
KW - Chronological age
KW - Puberty
KW - Salivary bone-specific alkaline phosphatase
UR - http://www.scopus.com/inward/record.url?scp=85075395527&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85075395527
SN - 1309-100X
VL - 12
SP - 1063
EP - 1067
JO - Journal of International Dental and Medical Research
JF - Journal of International Dental and Medical Research
IS - 3
ER -