TY - JOUR
T1 - Right ventricular outflow tract stenting for late presenter unrepaired Fallot physiology
T2 - a single-center experience
AU - Prakoso, Radityo
AU - Kurniawati, Yovi
AU - Siagian, Sisca Natalia
AU - Sembiring, Aditya Agita
AU - Sakti, Damba Dwisepto Aulia
AU - Mendel, Brian
AU - Pratiwi, Indah
AU - Lelya, Olfi
AU - Lilyasari, Oktavia
N1 - Publisher Copyright:
2024 Prakoso, Kurniawati, Siagian, Sembiring, Sakti, Mendel, Pratiwi, Lelya and Lilyasari.
PY - 2024
Y1 - 2024
N2 - Objectives: The purpose of this study was to assess the clinical outcome after right ventricular outflow tract (RVOT) stenting in late presenter patient with unrepaired Fallot physiology. Background: In younger patients, RVOT stenting is an alternative to mBTT shunt; however, there have been few reports of this palliative technique in late presenter population, including adults. Methods: This was a single-center, retrospective study of nonrandomized, palliated Fallot patients. Clinical outcomes such as left ventricular ejection fraction and saturation were measured in 32 individuals following RVOT stenting in adults (n = 10) and children (n = 22). The Statistical Package for Social Science (SPSS) 26.0 software was used to analyze the statistical data. Results: During the procedure, the average stent diameter and length were 8.84 ± 1.64 mm and 35.46 ± 11.23 mm, respectively. Adult patients received slightly longer stents than pediatric patients (43.60 ± 11.64 mm vs. 31.77 ± 9.07 mm). Overall, patients' saturation increased from 58.56 ± 19.03% to 91.03 ± 8.98% (p < 0.001), as did their left ventricular ejection fraction (LVEF) from 64.00 ± 18.21% to 75.09 ± 12.98% (p = 0.001). Three patients improved their LVEF from 31 to 55%, 31 to 67%, and 26 to 50%. The median length of stay was 8 (2–35) days, with an ICU stay of 2 (0–30) days. The median time from RVOT stent palliation to total repair was 3 months (range: 1 month–12 months). Conclusions: RVOT stenting is a safe and effective method for increasing saturation and ejection fraction not only in newborn infants but also in late presenters, including adults with unrepaired Fallot physiology.
AB - Objectives: The purpose of this study was to assess the clinical outcome after right ventricular outflow tract (RVOT) stenting in late presenter patient with unrepaired Fallot physiology. Background: In younger patients, RVOT stenting is an alternative to mBTT shunt; however, there have been few reports of this palliative technique in late presenter population, including adults. Methods: This was a single-center, retrospective study of nonrandomized, palliated Fallot patients. Clinical outcomes such as left ventricular ejection fraction and saturation were measured in 32 individuals following RVOT stenting in adults (n = 10) and children (n = 22). The Statistical Package for Social Science (SPSS) 26.0 software was used to analyze the statistical data. Results: During the procedure, the average stent diameter and length were 8.84 ± 1.64 mm and 35.46 ± 11.23 mm, respectively. Adult patients received slightly longer stents than pediatric patients (43.60 ± 11.64 mm vs. 31.77 ± 9.07 mm). Overall, patients' saturation increased from 58.56 ± 19.03% to 91.03 ± 8.98% (p < 0.001), as did their left ventricular ejection fraction (LVEF) from 64.00 ± 18.21% to 75.09 ± 12.98% (p = 0.001). Three patients improved their LVEF from 31 to 55%, 31 to 67%, and 26 to 50%. The median length of stay was 8 (2–35) days, with an ICU stay of 2 (0–30) days. The median time from RVOT stent palliation to total repair was 3 months (range: 1 month–12 months). Conclusions: RVOT stenting is a safe and effective method for increasing saturation and ejection fraction not only in newborn infants but also in late presenters, including adults with unrepaired Fallot physiology.
KW - adults
KW - ejection fraction
KW - late presenter
KW - palliative
KW - RVOT stent
KW - tetralogy of Fallot
UR - http://www.scopus.com/inward/record.url?scp=85185112740&partnerID=8YFLogxK
U2 - 10.3389/fcvm.2024.1340570
DO - 10.3389/fcvm.2024.1340570
M3 - Article
AN - SCOPUS:85185112740
SN - 2297-055X
VL - 11
JO - Frontiers in Cardiovascular Medicine
JF - Frontiers in Cardiovascular Medicine
M1 - 1340570
ER -