Review of biomolecular methods for age estimation in application of forensic odontology

Bambang Tri Hartomo, Nurtami Soedarsono, Angger Waspodo Dias Adrianto, Elza Ibrahim Auerkari

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Age estimation analysis can support the forensic identification for solving cases in the fields of law, anthropology, identification of victims of mass disasters, as well as in criminal cases. The molecular biology approach in predicting age is based on the principles of biomolecular changes as a person ages. In addition, usually, some of the evidence in criminal cases are biological material so that analysis through molecular biology approach is necessary. The method for biomolecular forensic analysis is divided into DNA-based methods that include mitochondrial DNA deletions, telomere shortening, circular excision of T-cell receptors (signal-joint-T-cell receptor excision circles, or sjTRECs), DNA methylation and protein-based methods which include advanced glycation end products, AGEs and aspartic acid racemization (AAR). This review aims to cover the current methods of molecular biology that are useful in predicting age in the applications of forensic odontology and identification.

Original languageEnglish
Title of host publication4th Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, Health, and Medical Devices
Subtitle of host publicationProceedings of the International Symposium of Biomedical Engineering, ISBE 2019
EditorsKenny Lischer, Tomy Abuzairi, Siti Fauziyah Rahman, Misri Gozan
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735419445
DOIs
Publication statusPublished - 10 Dec 2019
Event4th International Symposium of Biomedical Engineering�s Recent Progress in Biomaterials, Drugs Development, Health, and Medical Devices, ISBE 2019 - Padang, West Sumatera, Indonesia
Duration: 22 Jul 201924 Jul 2019

Publication series

NameAIP Conference Proceedings
Volume2193
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference4th International Symposium of Biomedical Engineering�s Recent Progress in Biomaterials, Drugs Development, Health, and Medical Devices, ISBE 2019
CountryIndonesia
CityPadang, West Sumatera
Period22/07/1924/07/19

Keywords

  • age estimation
  • Biomolecular analysis
  • DNA analysis
  • Forensic Odontology

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  • Cite this

    Hartomo, B. T., Soedarsono, N., Adrianto, A. W. D., & Auerkari, E. I. (2019). Review of biomolecular methods for age estimation in application of forensic odontology. In K. Lischer, T. Abuzairi, S. F. Rahman, & M. Gozan (Eds.), 4th Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, Health, and Medical Devices: Proceedings of the International Symposium of Biomedical Engineering, ISBE 2019 [040002] (AIP Conference Proceedings; Vol. 2193). American Institute of Physics Inc.. https://doi.org/10.1063/1.5139364