TY - GEN
T1 - Review of biomolecular methods for age estimation in application of forensic odontology
AU - Hartomo, Bambang Tri
AU - Soedarsono, Nurtami
AU - Adrianto, Angger Waspodo Dias
AU - Auerkari, Elza Ibrahim
N1 - Publisher Copyright:
© 2019 Author(s).
PY - 2019/12/10
Y1 - 2019/12/10
N2 - Age estimation analysis can support the forensic identification for solving cases in the fields of law, anthropology, identification of victims of mass disasters, as well as in criminal cases. The molecular biology approach in predicting age is based on the principles of biomolecular changes as a person ages. In addition, usually, some of the evidence in criminal cases are biological material so that analysis through molecular biology approach is necessary. The method for biomolecular forensic analysis is divided into DNA-based methods that include mitochondrial DNA deletions, telomere shortening, circular excision of T-cell receptors (signal-joint-T-cell receptor excision circles, or sjTRECs), DNA methylation and protein-based methods which include advanced glycation end products, AGEs and aspartic acid racemization (AAR). This review aims to cover the current methods of molecular biology that are useful in predicting age in the applications of forensic odontology and identification.
AB - Age estimation analysis can support the forensic identification for solving cases in the fields of law, anthropology, identification of victims of mass disasters, as well as in criminal cases. The molecular biology approach in predicting age is based on the principles of biomolecular changes as a person ages. In addition, usually, some of the evidence in criminal cases are biological material so that analysis through molecular biology approach is necessary. The method for biomolecular forensic analysis is divided into DNA-based methods that include mitochondrial DNA deletions, telomere shortening, circular excision of T-cell receptors (signal-joint-T-cell receptor excision circles, or sjTRECs), DNA methylation and protein-based methods which include advanced glycation end products, AGEs and aspartic acid racemization (AAR). This review aims to cover the current methods of molecular biology that are useful in predicting age in the applications of forensic odontology and identification.
KW - age estimation
KW - Biomolecular analysis
KW - DNA analysis
KW - Forensic Odontology
UR - http://www.scopus.com/inward/record.url?scp=85076719501&partnerID=8YFLogxK
U2 - 10.1063/1.5139364
DO - 10.1063/1.5139364
M3 - Conference contribution
AN - SCOPUS:85076719501
T3 - AIP Conference Proceedings
BT - 4th Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, Health, and Medical Devices
A2 - Lischer, Kenny
A2 - Abuzairi, Tomy
A2 - Rahman, Siti Fauziyah
A2 - Gozan, Misri
PB - American Institute of Physics Inc.
T2 - 4th International Symposium of Biomedical Engineering�s Recent Progress in Biomaterials, Drugs Development, Health, and Medical Devices, ISBE 2019
Y2 - 22 July 2019 through 24 July 2019
ER -
