Les troubles respiratoires et de coagulation à l’admission sont des facteurs indépendants de prédiction de mortalité chez brûlés hospitalisés en réanimation

Translated title of the contribution: Respiratory and coagulation dysfunctions on admission as independent predictors of in-hospital mortality in critically ill burn patients

Dita Aditianingsih, Y. B. Sinaga, W. Y. Kartolo, E. S. Adiwongso, A. S. Madjid

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Mortality rate for burns patients in developing countries is approximately 34%. Data show that most patients in burn units will likely experience organ dysfunction. Sequential Organ Failure Assessment (SOFA) score assesses organ dysfunction and is frequently used in the ICU, but there are no previous studies regarding SOFA score in burn units in Indonesia specifically. This study was a retrospective study, conducted to assess the validity of the SOFA score in predicting mortality of critically ill burn patients in the Burn HDU and ICU of Cipto Mangunkusumo General Hospital between January 2012 to December 2017. This study included 169 subjects who met the inclusion and exclusion criteria. Medical records were used to identify the sub-jects’ characteristics, SOFA score within 24 hours, and outcome (deceased or survived) at day 30. SOFA score validity was assessed using Area Under Curve (AUC), Hosmer-Lemeshow goodness of fit and multivariate logistic regression. The mortality rate for burn patients was 32.5%. SOFA score had very good discrimination (AUC 96.4%, CI 95% 0.933 – 0.995) and good calibration (Hosmer-Lemeshow p = 0.561). SOFA variables which had a statistically significant effect on 30-day mortality in the Burn Unit were PaO2/FiO2 ratio < 400, PaO2/FiO2 ratio < 300, PaO2/FiO2 ratio < 200 with mechanical ventilation and platelet count < 150,000/mm3. SOFA score was a valid instrument for predicting 30 day mortality of critically ill burn patients in the Burn HDU and ICU of Cipto Mangunkusumo General Hospital, especially respiration and coagulation variables.

Translated title of the contributionRespiratory and coagulation dysfunctions on admission as independent predictors of in-hospital mortality in critically ill burn patients
Original languageFrench
Pages (from-to)94-102
Number of pages9
JournalAnnals of Burns and Fire Disasters
Volume32
Issue number2
Publication statusPublished - 1 Jun 2019

Keywords

  • Burn
  • Mortality
  • Organ failure

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