Abstract
Optical sensor technology based on subwavelength periodic waveguides is applied for tag-free, high-resolution biomedical and chemical detection. Measured resonance wavelength shifts of 6.4 nm for chemically attached Bovine Serum Albumin agree well with theory for a sensor tested in air. Reflection peak efficiencies of 90% are measured, and do not degrade upon biolayer attachment. Phase detection methods are investigated to enhance sensor sensitivity and resolution. Direct measurement of the resonant phase response is reported for the first time using ellipsometric measurement techniques.
Original language | English |
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Article number | 11 |
Pages (from-to) | 52-57 |
Number of pages | 6 |
Journal | Proceedings of SPIE - The International Society for Optical Engineering |
Volume | 5515 |
DOIs | |
Publication status | Published - 2004 |
Event | Nanoengineering: Fabrication, Properties, Optics, and Devices - Denver, CO, United States Duration: 4 Aug 2004 → 6 Aug 2004 |
Keywords
- Biosensor
- Diffractive optics
- Guided-mode resonance effect
- Optical sensor