The challenge for engineer's orthopedic prosthetic rehabilitation is to find a state of the art in the field, technical or otherwise, that will help their clients who have disabilities. Organ replacement with prostheses is one of the most successful procedures until now. However prostheses are still using standard geometry that has been determined by the manufacturer of the prostheses and it becomes a problem. In addition to the design size that does not fit, long manufacturing process takes time and is expensive also being a problem. Suitability of the prostheses with the patient's body anthropometry and speed of production in the manufacture of the prostheses is very important. In manufacturing, precision and speed of manufacture of the product is something that is possible but requires a high cost, especially in the manufacture of prostheses. By using rapid prototyping technology are available, this research try to develop the customized and rapid manufacturing systems for the manufacture of prostheses, especially for Total Knee Replacement (TKR).