Abstract
Pyrazole is a five-membered heterocyclic compound containing two nitrogen atoms. Due to its biological significance, design of novel pyrazole derivatives has become an interesting research area. We report the current progress in the development of anticancer agents containing pyrazole ring covering the time span of the past few years (2013-2016). The presence of this nucleus is accompanied with some side chains, functional groups, or in combination with other nucleus such as thiazole, thiourea, glucosamine, naphthalimide, and benzofuran. Several biologically active pyrazoles synthesized by numerous researchers across the world are summarized in this paper.
| Original language | English |
|---|---|
| Pages (from-to) | 45-51 |
| Number of pages | 7 |
| Journal | Asian Journal of Pharmaceutical and Clinical Research |
| Volume | 10 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - 2017 |
Keywords
- Anticancer agents
- N-heterocyclic
- Pyrazole
- Synthetic derivatives