Recent progress and future challenge of high-capacity adsorbent for non-fission molybdenum-99 (99Mo) in application of 99Mo/99mTc generator

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Abstract

Technetium-99m (99mTc) plays a major role in diagnostic nuclear medicine and has not yet been replaced with any other radionuclides. The 99mTc is a decay product of molybdenum-99 (99Mo) and it is available through a 99Mo/99mTc generator. The 99Mo can be produced either from the fission reaction of uranium-235 or from neutron-irradiated of natural/enriched molybdenum-98. The non-fission 99Mo/99mTc generator has a low specific activity of 99Mo. This limitation, however, can be overcome by the use of high-capacity adsorbents for 99Mo. This review is focused on the current progress and future challenges in the development of high-capacity adsorbent materials for non-fission molybdenum-99 (99Mo) in the application of 99Mo/99mTc generator. We briefly summarized some materials as well as nanomaterials that show high adsorption capacity for non-fission 99Mo. We also highlighted several synthesis methods, including the green synthesis method using plant extracts which can be potentially used to obtain high-capacity adsorbent materials.

Original languageEnglish
Title of host publicationProceedings of the International Conference and School on Physics in Medicine and Biosystem, ICSPMB 2020
Subtitle of host publicationPhysics Contribution in Medicine and Biomedical Applications
EditorsLukmanda Evan Lubis, Nur Aisyah Nuzulia, Nur Rahmah Hidayati
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735440876
DOIs
Publication statusPublished - 29 Mar 2021
Event2020 International Conference and School on Physics in Medicine and Biosystem: Physics Contribution in Medicine and Biomedical Applications, ICSPMB 2020 - Depok, Virtual, Indonesia
Duration: 6 Nov 20208 Nov 2020

Publication series

NameAIP Conference Proceedings
Volume2346
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference2020 International Conference and School on Physics in Medicine and Biosystem: Physics Contribution in Medicine and Biomedical Applications, ICSPMB 2020
Country/TerritoryIndonesia
CityDepok, Virtual
Period6/11/208/11/20

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