Recent insight into potential acute respiratory distress syndrome

Zulkifli Amin, Fitriana N. Rahmawati

Research output: Contribution to journalReview articlepeer-review

5 Citations (Scopus)


Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung injury, characterized by increased pulmonary capillary endothelial cells and alveolar epithelial cells permeability leading to respiratory failure in the absence of cardiac failure. Despite recent advances in treatments, the overall mortality because of ARDS remains high. Biomarkers may help to diagnose, predict the severity, development, and outcome of ARDS in order to improve patient care and decrease morbidity and mortality. This review will focus on soluble receptor for advanced glycation end-products, soluble tumor necrosis factor-receptor 1, Interluken-6 (IL-6), IL-8, and plasminogen activator inhibitor-1, which have a greater potential based on recent studies.

Original languageEnglish
Pages (from-to)344-349
Number of pages6
JournalSaudi medical journal
Issue number4
Publication statusPublished - Apr 2017


  • ARDS
  • Biomarkers
  • Respiratory
  • Syndrome


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