Reactive oxygen species in osteoarthritis

Wahyu Widowati; Omat Rachmat; Tri Suciati; Dwi Davidson Rihibiha; Ervi Afifah; Tjandrawati Mozef; Rizal Rizal; Teresa Liliana Wargasetia; Sutiman B. Sumitro

Reactive oxygen species in osteoarthritis

Wahyu Widowati, Omat Rachmat, Tri Suciati, Dwi Davidson Rihibiha, Ervi Afifah, Tjandrawati Mozef, Rizal Rizal, Teresa Liliana Wargasetia, Sutiman B. Sumitro

Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Osteoarthritis is commonly the most joint disorder that rises with the aging of the population. The oxidative stress and overproduction of reactive oxygen species (ROS) are responsible for many process related to osteoarthritis such as the intracellular signaling process, apoptosis, extracellular matrix synthesis, dysfunction of the subchondral bone, and other processes. Thus far, drugs for osteoarthritis are still scarce, therefore targeting the complex oxidative stress signaling pathways would be a potential strategy in finding treatment of this disease.

Original language	English
Title of host publication	Reactive Oxygen Species (ROS)
Subtitle of host publication	Mechanisms and Role in Health and Disease
Publisher	Nova Science Publishers, Inc.
Pages	135-175
Number of pages	41
ISBN (Electronic)	9781536131673
ISBN (Print)	9781536131666
Publication status	Published - 1 Jan 2018

Cite this

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AU - Widowati, Wahyu

AU - Rachmat, Omat

AU - Suciati, Tri

AU - Rihibiha, Dwi Davidson

AU - Afifah, Ervi

AU - Mozef, Tjandrawati

AU - Rizal, Rizal

AU - Wargasetia, Teresa Liliana

AU - Sumitro, Sutiman B.

PY - 2018/1/1

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AB - Osteoarthritis is commonly the most joint disorder that rises with the aging of the population. The oxidative stress and overproduction of reactive oxygen species (ROS) are responsible for many process related to osteoarthritis such as the intracellular signaling process, apoptosis, extracellular matrix synthesis, dysfunction of the subchondral bone, and other processes. Thus far, drugs for osteoarthritis are still scarce, therefore targeting the complex oxidative stress signaling pathways would be a potential strategy in finding treatment of this disease.

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BT - Reactive Oxygen Species (ROS)

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ER -

Reactive oxygen species in osteoarthritis

Abstract

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