Reactive oxygen species as inducers and inhibitors of cancer

Wahyu Widowati; Ahmad Faried; Rachmawati Noverina; Wireni Ayuningtyas; Dedy Kurniawan; Dwi Davidson Rihibiha; Rizal Rizal; Teresa Liliana Wargasetia; M. Aris Widodo

Reactive oxygen species as inducers and inhibitors of cancer

Wahyu Widowati, Ahmad Faried, Rachmawati Noverina, Wireni Ayuningtyas, Dedy Kurniawan, Dwi Davidson Rihibiha, Rizal Rizal, Teresa Liliana Wargasetia, M. Aris Widodo

Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Reactive oxygen species or ROS is formed in vivo and many of them are considered as strong oxidizing agents, and it's capable in destruction DNA and other biomolecules. Elevated ROS production generates development of malignancy. Moreover, the 'normal' rates of ROS generation may play a role in the increased risk of cancer development. Indeed, the knockout of various antioxidant defense enzymes raises oxidative damage levels and promotes age-related cancer development in animals. Many recent studies have been focusing on direct oxidative damage to DNA by certain ROS, such as hydroxyl radical (OH*).

Original language	English
Title of host publication	Reactive Oxygen Species (ROS)
Subtitle of host publication	Mechanisms and Role in Health and Disease
Publisher	Nova Science Publishers, Inc.
Pages	177-206
Number of pages	30
ISBN (Electronic)	9781536131673
ISBN (Print)	9781536131666
Publication status	Published - 1 Jan 2018

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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author = "Wahyu Widowati and Ahmad Faried and Rachmawati Noverina and Wireni Ayuningtyas and Dedy Kurniawan and Rihibiha, {Dwi Davidson} and Rizal Rizal and Wargasetia, {Teresa Liliana} and Widodo, {M. Aris}",

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T1 - Reactive oxygen species as inducers and inhibitors of cancer

AU - Widowati, Wahyu

AU - Faried, Ahmad

AU - Noverina, Rachmawati

AU - Ayuningtyas, Wireni

AU - Kurniawan, Dedy

AU - Rihibiha, Dwi Davidson

AU - Rizal, Rizal

AU - Wargasetia, Teresa Liliana

AU - Widodo, M. Aris

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Reactive oxygen species or ROS is formed in vivo and many of them are considered as strong oxidizing agents, and it's capable in destruction DNA and other biomolecules. Elevated ROS production generates development of malignancy. Moreover, the 'normal' rates of ROS generation may play a role in the increased risk of cancer development. Indeed, the knockout of various antioxidant defense enzymes raises oxidative damage levels and promotes age-related cancer development in animals. Many recent studies have been focusing on direct oxidative damage to DNA by certain ROS, such as hydroxyl radical (OH*).

AB - Reactive oxygen species or ROS is formed in vivo and many of them are considered as strong oxidizing agents, and it's capable in destruction DNA and other biomolecules. Elevated ROS production generates development of malignancy. Moreover, the 'normal' rates of ROS generation may play a role in the increased risk of cancer development. Indeed, the knockout of various antioxidant defense enzymes raises oxidative damage levels and promotes age-related cancer development in animals. Many recent studies have been focusing on direct oxidative damage to DNA by certain ROS, such as hydroxyl radical (OH*).

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M3 - Chapter

AN - SCOPUS:85048845471

SN - 9781536131666

SP - 177

EP - 206

BT - Reactive Oxygen Species (ROS)

PB - Nova Science Publishers, Inc.

ER -

Reactive oxygen species as inducers and inhibitors of cancer

Abstract

UN SDGs

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