Reactive oxygen species and aging mechanism

Wahyu Widowati; Rachmawati Noverina; Wireni Ayuningtyas; Dedy Kurniawan; Ahmad Faried; Dian Ratih Laksmitawati; Dwi Davidson Rihibiha; Rizal Rizal; Tri Suciati; Sutiman B. Sumitro

Reactive oxygen species and aging mechanism

Wahyu Widowati, Rachmawati Noverina, Wireni Ayuningtyas, Dedy Kurniawan, Ahmad Faried, Dian Ratih Laksmitawati, Dwi Davidson Rihibiha, Rizal Rizal, Tri Suciati, Sutiman B. Sumitro

Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Citation (Scopus)

Abstract

Skin aging is a complex process affected by both genetic and environmental factors, and it is caused by the cumulative damage from exposure to ultraviolet (UV) radiation. Chronic exposure to UV radiation on human skin further generates solar elastosis, degradation of the extracellular matrix (ECM), and wrinkle formation. UV radiation exposure leads to production of reactive oxygen species (ROS) in the skin. Chronological & photo-aging occurred via ROS by cascade signaling pathways. Treatment of antioxidants is an effective approach to prevent symptoms related to photo-induced skin aging. In this chapter, the mechanisms of ROS generation in the skin, the roles of ROS in altering the skin and ROS elimination in the body are discussed.

Original language	English
Title of host publication	Reactive Oxygen Species (ROS)
Subtitle of host publication	Mechanisms and Role in Health and Disease
Publisher	Nova Science Publishers, Inc.
Pages	101-134
Number of pages	34
ISBN (Electronic)	9781536131673
ISBN (Print)	9781536131666
Publication status	Published - 1 Jan 2018

Cite this

@inbook{7af8a171247a491bb5a303fe6f95542f,

title = "Reactive oxygen species and aging mechanism",

abstract = "Skin aging is a complex process affected by both genetic and environmental factors, and it is caused by the cumulative damage from exposure to ultraviolet (UV) radiation. Chronic exposure to UV radiation on human skin further generates solar elastosis, degradation of the extracellular matrix (ECM), and wrinkle formation. UV radiation exposure leads to production of reactive oxygen species (ROS) in the skin. Chronological & photo-aging occurred via ROS by cascade signaling pathways. Treatment of antioxidants is an effective approach to prevent symptoms related to photo-induced skin aging. In this chapter, the mechanisms of ROS generation in the skin, the roles of ROS in altering the skin and ROS elimination in the body are discussed.",

author = "Wahyu Widowati and Rachmawati Noverina and Wireni Ayuningtyas and Dedy Kurniawan and Ahmad Faried and Laksmitawati, {Dian Ratih} and Rihibiha, {Dwi Davidson} and Rizal Rizal and Tri Suciati and Sumitro, {Sutiman B.}",

year = "2018",

month = jan,

day = "1",

language = "English",

isbn = "9781536131666",

pages = "101--134",

booktitle = "Reactive Oxygen Species (ROS)",

publisher = "Nova Science Publishers, Inc.",

address = "United States",

}

TY - CHAP

T1 - Reactive oxygen species and aging mechanism

AU - Widowati, Wahyu

AU - Noverina, Rachmawati

AU - Ayuningtyas, Wireni

AU - Kurniawan, Dedy

AU - Faried, Ahmad

AU - Laksmitawati, Dian Ratih

AU - Rihibiha, Dwi Davidson

AU - Rizal, Rizal

AU - Suciati, Tri

AU - Sumitro, Sutiman B.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Skin aging is a complex process affected by both genetic and environmental factors, and it is caused by the cumulative damage from exposure to ultraviolet (UV) radiation. Chronic exposure to UV radiation on human skin further generates solar elastosis, degradation of the extracellular matrix (ECM), and wrinkle formation. UV radiation exposure leads to production of reactive oxygen species (ROS) in the skin. Chronological & photo-aging occurred via ROS by cascade signaling pathways. Treatment of antioxidants is an effective approach to prevent symptoms related to photo-induced skin aging. In this chapter, the mechanisms of ROS generation in the skin, the roles of ROS in altering the skin and ROS elimination in the body are discussed.

AB - Skin aging is a complex process affected by both genetic and environmental factors, and it is caused by the cumulative damage from exposure to ultraviolet (UV) radiation. Chronic exposure to UV radiation on human skin further generates solar elastosis, degradation of the extracellular matrix (ECM), and wrinkle formation. UV radiation exposure leads to production of reactive oxygen species (ROS) in the skin. Chronological & photo-aging occurred via ROS by cascade signaling pathways. Treatment of antioxidants is an effective approach to prevent symptoms related to photo-induced skin aging. In this chapter, the mechanisms of ROS generation in the skin, the roles of ROS in altering the skin and ROS elimination in the body are discussed.

UR - http://www.scopus.com/inward/record.url?scp=85048844743&partnerID=8YFLogxK

M3 - Chapter

AN - SCOPUS:85048844743

SN - 9781536131666

SP - 101

EP - 134

BT - Reactive Oxygen Species (ROS)

PB - Nova Science Publishers, Inc.

ER -

Reactive oxygen species and aging mechanism

Abstract

Other files and links

Fingerprint

Cite this