Rapid diagnosis of thyroid fever through identification of Salmonella typhi within 18 hours of specimen acquisition by culture of the mononuclear cell-platelet fraction of blood

F. A. Rubin, P. D. McWhirter, D. Burr, N. H. Punjabi, E. Lane, S. Kumala, Pratiwi Pudjilestari Sudarmono, S. Pandam Pulungshi, M. Lesmana, P. Tjaniadi, N. Sukri, S. L. Hoffman

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

Detection of Salmonella typhi in blood by culture of the mononuclear cell-platelet layer was compared with other methods currently used for the diagnosis of typhoid fever. Colonies of S. typhi were present in all mononuclear cell-platelet layer-positive cultures within 18 h of plating and were identified within an additional 10 min by a coagglutination technique. In contrast, identification of all positive cultures by conventional blood culture required 3 days.

Original languageEnglish
Pages (from-to)825-827
Number of pages3
JournalJournal of Clinical Microbiology
Volume28
Issue number4
DOIs
Publication statusPublished - 1990

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