Rapid advancement in cancer genomic big data in the pursuit of precision oncology

Research output: Contribution to journalReview articlepeer-review

Abstract

In the current big data era, massive genomic cancer data are available for open access from anywhere in the world. They are obtained from popular platforms, such as The Cancer Genome Atlas, which provides genetic information from clinical samples, and Cancer Cell Line Encyclopedia, which offers genomic data of cancer cell lines. For convenient analysis, user-friendly tools, such as the Tumor Immune Estimation Resource (TIMER), which can be used to analyze tumor-infiltrating immune cells comprehensively, are also emerging. In clinical practice, clinical sequencing has been recommended for patients with cancer in many countries. Despite its many challenges, it enables the application of precision medicine, especially in medical oncology. In this review, several efforts devoted to accomplishing precision oncology and applying big data for use in Indonesia are discussed. Utilizing open access genomic data in writing research articles is also described.

Original languageEnglish
Pages (from-to)81-85
Number of pages5
JournalMedical Journal of Indonesia
Volume30
Issue number1
DOIs
Publication statusPublished - 2021

Keywords

  • Cancer genetic database
  • Oncology
  • Personalized medicine

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