TY - JOUR
T1 - Quality of Antibotic Prescribing for Respiratory Tract Disease in Primary Healthcare Centers in Tegal Regency, Central Java, Indonesia
AU - Radji, Maksum
PY - 2020
Y1 - 2020
N2 - The prescription of antibiotics for diagnosed upper respiratory tract infections (URTIs) is frequently
practiced. Furthermore, inappropriate use has been implicated in numerous problems, including the onset
of resistance. This study is, therefore, aimed to evaluate the antibiotic prescribing quality for respiratory
tract disease diagnosed at the outpatients of primary healthcare centers in Tegal District, Central
Java, Indonesia. In addition, cross-sectional evaluation was employed, using data obtained within the
period of June–August, 2018 in six locations, and subsequently subjected to qualitative analysis. The
prescribing quality was evaluated by comparing the drug selected, dosage, frequency, and duration of
administration stated in the prescriptions, with the terms in the Clinical Practice Guidelines for Primary
Healthcare Facilities, 2014. A total of 1453 samples were selected through purposive sampling, where
632 were diagnosed with respiratory tract diseases, with common cold as the most frequent diagnosis
(87.2%). In addition, exactly 621 (98.3%) failed to fulfill the rational antibiotic prescribing criteria,
evidenced by irrational drug selection (22.0%), dosage (9.5%), frequency (1.7%), and duration of
administration (65.0%). The physicians tend to comply more with the national treatment guidelines
(OR: 1.828, 95%CI: 0.486–6.874, p-value 0.365), and the less experience of prescribers (<12 years
of service) was identified as a negative contributing factor (OR: 0.536, 95%CI: 0.143–2.016, p-value
0.349). Furthermore, irrational prescription was observed in a much larger proportion, influenced by the
prescribers’ qualification and experience. This association is currently not significant, due to deficiency
of influencing samples
AB - The prescription of antibiotics for diagnosed upper respiratory tract infections (URTIs) is frequently
practiced. Furthermore, inappropriate use has been implicated in numerous problems, including the onset
of resistance. This study is, therefore, aimed to evaluate the antibiotic prescribing quality for respiratory
tract disease diagnosed at the outpatients of primary healthcare centers in Tegal District, Central
Java, Indonesia. In addition, cross-sectional evaluation was employed, using data obtained within the
period of June–August, 2018 in six locations, and subsequently subjected to qualitative analysis. The
prescribing quality was evaluated by comparing the drug selected, dosage, frequency, and duration of
administration stated in the prescriptions, with the terms in the Clinical Practice Guidelines for Primary
Healthcare Facilities, 2014. A total of 1453 samples were selected through purposive sampling, where
632 were diagnosed with respiratory tract diseases, with common cold as the most frequent diagnosis
(87.2%). In addition, exactly 621 (98.3%) failed to fulfill the rational antibiotic prescribing criteria,
evidenced by irrational drug selection (22.0%), dosage (9.5%), frequency (1.7%), and duration of
administration (65.0%). The physicians tend to comply more with the national treatment guidelines
(OR: 1.828, 95%CI: 0.486–6.874, p-value 0.365), and the less experience of prescribers (<12 years
of service) was identified as a negative contributing factor (OR: 0.536, 95%CI: 0.143–2.016, p-value
0.349). Furthermore, irrational prescription was observed in a much larger proportion, influenced by the
prescribers’ qualification and experience. This association is currently not significant, due to deficiency
of influencing samples
M3 - Article
SN - 2252-6218
JO - Indonesian Journal of Clinical Pharmacy
JF - Indonesian Journal of Clinical Pharmacy
ER -