TY - JOUR
T1 - Pulmonary alveolar proteinosis with secondary Aspergillus infection
T2 - A case report
AU - Fachrucha, Fanny
AU - Andarini, Sita
AU - Elhidsi, Mia
AU - Irawan, Rizky Yudha
AU - Beginta, Romi
AU - Sutoyo, Dianiati Kusumo
N1 - Publisher Copyright:
© 2022 Fachrucha, et al.; licensee University of Sarajevo - Faculty of Health Studies
PY - 2021
Y1 - 2021
N2 - Pulmonary alveolar proteinosis (PAP) is a rare disease with mostly due to autoimmune toward granulocyte-macropahge colony-stimulating factor. In some conditions, PAP followed with secondary infection. A 34-year-old woman came with progressive shortness of breath, chronic dry cough, and mild fever. The chest High-Resolution Computed Tomography showed ground-glass opacity with septal reticulation or known as the crazy-paving pattern, and a cavity on the upper lobe of the left lung. The patient underwent bronchoscopy for diagnostic and therapeutic measures and found milky appearance bronchoalveolar lavage fluid (BALF). The serum galactomannan came out positive. Fungal infection detected from the BALF culture, Aspergillus fumigatus, hence fulfilling the diagnosis of PAP with probable invasive pulmonary aspergillosis. The patient showed clinical improvement after undergoing whole lung lavage and given anti-fungal medications
AB - Pulmonary alveolar proteinosis (PAP) is a rare disease with mostly due to autoimmune toward granulocyte-macropahge colony-stimulating factor. In some conditions, PAP followed with secondary infection. A 34-year-old woman came with progressive shortness of breath, chronic dry cough, and mild fever. The chest High-Resolution Computed Tomography showed ground-glass opacity with septal reticulation or known as the crazy-paving pattern, and a cavity on the upper lobe of the left lung. The patient underwent bronchoscopy for diagnostic and therapeutic measures and found milky appearance bronchoalveolar lavage fluid (BALF). The serum galactomannan came out positive. Fungal infection detected from the BALF culture, Aspergillus fumigatus, hence fulfilling the diagnosis of PAP with probable invasive pulmonary aspergillosis. The patient showed clinical improvement after undergoing whole lung lavage and given anti-fungal medications
KW - Fungal infection
KW - Milky appearance bronchoalveolar lavage fluid
KW - Pulmonary alveolar proteinosis
KW - Whole lung lavage
UR - http://www.scopus.com/inward/record.url?scp=85123527299&partnerID=8YFLogxK
U2 - 10.17532/JHSCI.2021.1366
DO - 10.17532/JHSCI.2021.1366
M3 - Article
AN - SCOPUS:85123527299
VL - 11
SP - 191
EP - 195
JO - Journal of Health Sciences
JF - Journal of Health Sciences
SN - 2232-7576
IS - 3
ER -