TY - JOUR
T1 - Psychological Burden among Pediatric Thalassemia Major Patients in Indonesia: A Review
AU - Sari, Teny Tjitra
AU - Rahmartani, Ludi Dhyani
AU - Wirahmadi, Angga
AU - Selene, Nathasha Brigitta
AU - Iskandar, Stephen Diah
AU - Wahidiyat, Pustika Amalia
PY - 2024
Y1 - 2024
N2 - Thalassemia a common hereditary blood disorder resulting in anemia. It is an important public health problem, with a high prevalence in Southeast Asia and Mediterranean countries, and preventable through screening programs. However, due to its chronic nature, permanent physical changes, troublesome complications, and lifelong treatment, pediatric patients with thalassemia major are more prone to mental disorders and cognitive impairment. Internalizing and externalizing problems are higher in pediatric patients with thalassemia. Children with β-thalassemia major exhibit lower IQ scores than healthy children. Neurophysiology and neuroimaging examinations have shown abnormal results in children with thalassemia. Co-morbidity with mental disorders increases the mortality, morbidity, and total healthcare costs of patients with thalassemia. Therefore, routine evaluation of mental health problems is recommended to accommodate the early detection and prompt treatment of mental disorders. A multidisciplinary approach for thalassemia patients and families should be delivered by providing appropriate medical care, psychosocial support, and good transition care to improve survival and well-being, assist good social integration and daily functioning, and cope with the stress of chronic disease.
AB - Thalassemia a common hereditary blood disorder resulting in anemia. It is an important public health problem, with a high prevalence in Southeast Asia and Mediterranean countries, and preventable through screening programs. However, due to its chronic nature, permanent physical changes, troublesome complications, and lifelong treatment, pediatric patients with thalassemia major are more prone to mental disorders and cognitive impairment. Internalizing and externalizing problems are higher in pediatric patients with thalassemia. Children with β-thalassemia major exhibit lower IQ scores than healthy children. Neurophysiology and neuroimaging examinations have shown abnormal results in children with thalassemia. Co-morbidity with mental disorders increases the mortality, morbidity, and total healthcare costs of patients with thalassemia. Therefore, routine evaluation of mental health problems is recommended to accommodate the early detection and prompt treatment of mental disorders. A multidisciplinary approach for thalassemia patients and families should be delivered by providing appropriate medical care, psychosocial support, and good transition care to improve survival and well-being, assist good social integration and daily functioning, and cope with the stress of chronic disease.
KW - thalassemia major
KW - psychosocial burden
KW - early detection
KW - psychosocial support
UR - https://www.mdpi.com/2039-4365/14/2/5
U2 - 10.3390/thalassrep14020005
DO - 10.3390/thalassrep14020005
M3 - Review article
SN - 2039-4365
VL - 14
SP - 33
EP - 43
JO - Thalassemia Reports
JF - Thalassemia Reports
IS - 2
ER -