@inproceedings{df0dcbbafa734570aa9e7871aa25ca16,
title = "Protein sequences clustering of herpes virus by using Tribe Markov clustering (Tribe-MCL)",
abstract = "The herpes virus can be found anywhere and one of the important characteristics is its ability to cause acute and chronic infection at certain times so as a result of the infection allows severe complications occurred. The herpes virus is composed of DNA containing protein and wrapped by glycoproteins. In this work, the Herpes viruses family is classified and analyzed by clustering their protein-sequence using Tribe Markov Clustering (Tribe-MCL) algorithm. Tribe-MCL is an efficient clustering method based on the theory of Markov chains, to classify protein families from protein sequences using pre-computed sequence similarity information. We implement the Tribe-MCL algorithm using an open source program of R. We select 24 protein sequences of Herpes virus obtained from NCBI database. The dataset consists of three types of glycoprotein B, F, and H. Each type has eight herpes virus that infected humans. Based on our simulation using different inflation factor r=1.5, 2, 3 we find a various number of the clusters results. The greater the inflation factor the greater the number of their clusters. Each protein will grouped together in the same type of protein.",
keywords = "Clustering, Herpes Virus Sequence of Protein, Tribe Markov Clustering, Tribe-MCL",
author = "A. Bustamam and T. Siswantining and Febriyani, {N. L.} and Novitasari, {I. D.} and Cahyaningrum, {R. D.}",
note = "Publisher Copyright: {\textcopyright} 2017 Author(s).; 2nd International Symposium on Current Progress in Mathematics and Sciences 2016, ISCPMS 2016 ; Conference date: 01-11-2016 Through 02-11-2016",
year = "2017",
month = jul,
day = "10",
doi = "10.1063/1.4991254",
language = "English",
series = "AIP Conference Proceedings",
publisher = "American Institute of Physics Inc.",
editor = "Sugeng, {Kiki Ariyanti} and Djoko Triyono and Terry Mart",
booktitle = "International Symposium on Current Progress in Mathematics and Sciences 2016, ISCPMS 2016",
address = "United States",
}