Multizentrischie Prospektive Studie zur Quantifizierung des HRT-Effekts auf das Bindegeweble Durch Kollagenmessung Mittels Osteoson®-Collagenoson

Translated title of the contribution: Prospective Multicentre Study for Quantification of HRT Effect on Connective Tissue by Collagen Measurement with Osteoson®-Collagenoson

W. Barchasch, Ali Baziad, B. Fervers-Schorre, J. Huber, K. Keck, J. Pferdmenges, Jobst Wedegärtner

Research output: Contribution to journalArticlepeer-review

Abstract

228 hormone substituted female patients and 135 unsubstituted healthy volunteers have been compared concerning the state of their connective tissue. Quality control on connective tissue was conducted with the help of the high resolution ultrasonic test equipment Osteoson®-Collagenoson (Minhorst, Germany). Relative changes of the mean values of the skin thickness have been determined numerically and polynomially. Within 2 years a highly significant increase of skin thickness (0.071 mm; p < 0.01) on peri- and postmenopausal women treated with hormones was measured while a significant decrease of skin thickness (0.035 mm) on the controls was measured within the same period of time. Thus, with the HF-ultrasound-skin-thickness test equipment the excitation of collagen regeneration as well as the HRT-balancing effect on collagen deficiency is quantifiable objectively.

Translated title of the contributionProspective Multicentre Study for Quantification of HRT Effect on Connective Tissue by Collagen Measurement with Osteoson®-Collagenoson
Original languageGerman
Pages (from-to)22-24
Number of pages3
JournalJournal fur Menopause
Volume11
Issue number1
Publication statusPublished - 2 Apr 2004

Keywords

  • Collagen
  • Collagen measurement
  • Connective tissue
  • Hormone deficiency
  • Hormone replacement

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