Prophylactic antibiotics alone versus combined prophylaxis and postoperative antibiotics for preventing surgical-site infections associated with ear and nose reconstructive surgery

Trimartani Koento, Rangga R. Saleh

Research output: Contribution to journalArticle

Abstract

Objective: The aim of this study was to acquire supporting data for the rational use of antibiotics in plastic reconstructive surgery in the Ear-Nose-Throat/Head and Neck Surgery Department at Cipto Mangunkusumo Hospital–Faculty of Medicine Indonesia University. Methods: This pilot study, with a negative trial design, included 12 subjects who were randomly divided into two groups: Preoperative prophylactic antibiotic-only group and a combination of prophylactic and postoperative antibiotic group (controls). Results: The results showed that only 1 of the 12 subjects (in the prophylactic antibiotic-only group) developed an SSI. None of the controls (combined-use group) had an SSI. The difference between the two groups was not significant. Conclusion: The use of postoperative antibiotic appears not to be necessary in plastic reconstructive surgery patients to prevent SSIs. Further study, however, is required to support the findings of this study.

Original languageEnglish
Pages (from-to)37-41
Number of pages5
JournalInternational Journal of Applied Pharmaceutics
Volume11
Issue numberSpecial Issue 6
DOIs
Publication statusPublished - Nov 2019

Keywords

  • Ear reconstructive surgery
  • Nose reconstructive surgery
  • Postoperative antibiotic
  • Prophylactic antibiotic
  • Surgical-site infection

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