Production of flavonoid compounds from mother in law's tongue leaves (Sansevieria trifasciata) using microwave-assisted enzymatic extraction as anti-inflammatory

A. Megantika, A. T. Adhityaxena, R. Arbianti, T. S. Utami, H. Hermansyah

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Dysmenorrhea (menstrual cramps) is defined as difficult menstrual flow or painful menstruation and the most important cause of chronic pelvic pain. It caused by an increase in prostaglandin which has an inflammatory and painful effect. Flavonoids are constituents that can inhibit the formation of prostaglandins. In this study, extraction of flavonoid compounds from mother in law's tongue (Sansevieria trifasciata) leaves was evaluated using Microwave-Assisted Enzymatic Extraction (MAEE) method. The optimal extraction conditions were as follows: enzyme concentration 40 mg/100 mL distilled water and 70% ethanol concentration. Under these conditions, the extraction yield of S. trifasciata achieved was 42.53%, which represented an increase of 83%, respectively, compared with the control experiment (23.27%). The flavonoid content at optimum MAEE conditions reached 0.52 mg/g extract, while the control only obtained 0.32 mg/g extract. Anti-inflammatory activity test of mother in law's tongue leaves was done using in vivo method in white male rats (Rattus norvegicus). The inhibition percentage showed that S. trifasciata extract (500 mg/kg BB) was potential to inhibit anti-inflammatory activity by 70.32% relative to Na Diclofenac as a positive control. This results concluded that MAEE methods was an effective extraction method to improved extraction yield and flavonoid content of S. trifasciata which can be used for anti-inflammatory conditions such as menstrual cramps.

Original languageEnglish
Title of host publication4th International Tropical Renewable Energy Conference, i-TREC 2019
EditorsEny Kusrini, I. Gde Dharma Nugraha
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735420144
DOIs
Publication statusPublished - 3 Sep 2020
Event4th International Tropical Renewable Energy Conference 2019, i-TREC 2019 - Bali, Indonesia
Duration: 14 Aug 201916 Aug 2019

Publication series

NameAIP Conference Proceedings
Volume2255
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference4th International Tropical Renewable Energy Conference 2019, i-TREC 2019
CountryIndonesia
CityBali
Period14/08/1916/08/19

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