Primary prophylaxis of gastroesophageal variceal bleeding: Consensus recommendations of the Asian Pacific Association for the Study of the Liver

Shiv Kumar Sarin, Ashish Kumar, Peter W. Angus, Sanjay Saran Baijal, Yogesh Kumar Chawla, Radha Krishna Dhiman, H. Janaka de Silva, Saeed Hamid, Shozo Hirota, Ming Chih Hou, Wasim Jafri, Mobin Khan, Laurentius M. Adrianto Lesmana, Hock F. Lui, Veena Malhotra, Hitoshi Maruyama, Debendranath Guha Mazumder, Masao Omata, Ujjal Poddar, Amrinder S. PuriPraveen Sharma, Huma Qureshi, Rizvi Moattar Raza, Peush Sahni, Puja Sakhuja, Mohammad Salih, Amal Santra, Barjesh Chander Sharma, Hasnain Ali Shah, Gamal Shiha, Jose Sollano

Research output: Contribution to journalReview articlepeer-review

27 Citations (Scopus)

Abstract

The Asian Pacific Association for the Study of the Liver (APASL) set up a Working Party on Portal Hypertension in 2002, with a mandate to develop consensus guidelines on various clinical aspects of portal hypertension relevant to disease patterns and clinical practice in the Asia-Pacific region. Variceal bleeding is a consequence of portal hypertension, which, in turn, is the major complication of liver cirrhosis. Primary prophylaxis to prevent the first bleed from varices is one of the most important strategies for reducing the mortality in cirrhotic patients. Experts predominantly from the Asia-Pacific region were requested to identify the different aspects of primary prophylaxis and develop the consensus guidelines. The APASL Working Party on Portal Hypertension evaluated the various therapies that have been used for the prevention of first variceal bleeding. A 2-day meeting was held on January 12 and 13, 2007, at New Delhi, India, to discuss and finalize the consensus statements. Only those statements that were unanimously approved by the experts were accepted. These statements were circulated to all the experts and were subsequently presented at the annual conference of the APASL at Kyoto, Japan, in March 2007.

Original languageEnglish
Pages (from-to)429-439
Number of pages11
JournalHepatology International
Volume2
Issue number4
DOIs
Publication statusPublished - 8 Sep 2008

Keywords

  • Cirrhosis
  • GI bleed
  • Guidelines
  • Varices

Fingerprint Dive into the research topics of 'Primary prophylaxis of gastroesophageal variceal bleeding: Consensus recommendations of the Asian Pacific Association for the Study of the Liver'. Together they form a unique fingerprint.

Cite this