Primární lymfom prsu – kazuistika

Translated title of the contribution: Primary breast lymphoma – a case report

W. Rajabto, Y. Kusuma Angkasa, A. S. Harahap, M. F. Ham, B. Brahma

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Primary breast lymphoma is a rare disease and accounts for 0.4–0.5% of malignant breast neoplasms and 1.7–2.2% of extra-nodal lymphomas, with diffuse large B-cell lymphoma (DLBCL) as the most common histologic subtype. Case: A 47-year-old female with beta thalassemia presented with a lump of the left breast, redness, pain, and swelling of her left breast. Physical examination showed tender, red, swollen left breast. Laboratory findings show mild anemia and normal level of lactate dehydrogenase 329 U/L (normal range: 240–480 U/L). PET scan showed hypermetabolic mass with irregular margins covering the whole left breast quadrants with the size of 11.25 × 5.17 cm with left pectoralis major, left parasternal, and left axillary hypermetabolic nodules. Histopathology and immunohistochemistry staining showed a non-germinal center B-cell-like subtype of DLBCL CD20+. We administered the R-CHOP regi-men (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednison) every 3 weeks for 6 cycles. The response was complete remission. The patient tolerated the chemotherapy well and achieved long term complete remission. Conclusion: Primary breast lymphoma is a rare disease with the most common subtype is diffuse large B-cell lymphoma. Systemic chemotherapy R-CHOP is the treatment option for primary breast diffuse large B-cell lymphoma.

Translated title of the contributionPrimary breast lymphoma – a case report
Original languageUndefined/Unknown
Pages (from-to)477-480
Number of pages4
JournalKlinicka Onkologie
Volume34
Issue number6
DOIs
Publication statusPublished - 2021

Keywords

  • Diffuse large B-cell lymphoma
  • Primary breast lymphoma
  • R-CHOP chemotherapy

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