TY - JOUR
T1 - Prevention and Management of Iron Deficiency/Iron-Deficiency Anemia in Women
T2 - An Asian Expert Consensus
AU - Pai, Rishma Dhillon
AU - Chong, Yap Seng
AU - Clemente-Chua, Lyra Ruth
AU - Irwinda, Rima
AU - Huynh, Trang Nguyen Khanh
AU - Wibowo, Noroyono
AU - Gamilla, Maria Corazon Zaida
AU - Mahdy, Zaleha Abdullah
N1 - Funding Information:
Procter & Gamble Health.
Publisher Copyright:
© 2023 by the authors.
PY - 2023/7
Y1 - 2023/7
N2 - The lack of standardized clinical practice impeding the optimal management of iron deficiency (ID) and iron deficiency anemia (IDA) in women is a global concern, particularly in the Asia-Pacific region. The aim of this study was to determine best practices through a Delphi consensus process. In Round 1, panelists were asked to rate their level of agreement with 99 statements across four domains: identification, diagnosis and assessment, prevention, and treatment of ID/IDA in women. In Round 2, panelists reappraised their ratings in view of the collective feedback and responses to Round 1. After two rounds, consensus (≥85% agreement) was reached for 84% of the Delphi statements. Experts agreed on the role of presenting symptoms and risk factors in prompting assessments of anemia and iron status in women. Experts repeatedly called for prevention, recommending preventive iron supplementation for pregnant women irrespective of anemia prevalence levels, and for non-pregnant adult women, adolescent girls, and perimenopausal women living in areas with a high prevalence of anemia. Experts unanimously agreed to prescribing oral ferrous iron as first-line therapy for uncomplicated ID/IDA. The recommendations and clinical pathway algorithms generated should be used to inform clinical practice and standardize the care of women at risk or presenting with ID/IDA in the Asia-Pacific region.
AB - The lack of standardized clinical practice impeding the optimal management of iron deficiency (ID) and iron deficiency anemia (IDA) in women is a global concern, particularly in the Asia-Pacific region. The aim of this study was to determine best practices through a Delphi consensus process. In Round 1, panelists were asked to rate their level of agreement with 99 statements across four domains: identification, diagnosis and assessment, prevention, and treatment of ID/IDA in women. In Round 2, panelists reappraised their ratings in view of the collective feedback and responses to Round 1. After two rounds, consensus (≥85% agreement) was reached for 84% of the Delphi statements. Experts agreed on the role of presenting symptoms and risk factors in prompting assessments of anemia and iron status in women. Experts repeatedly called for prevention, recommending preventive iron supplementation for pregnant women irrespective of anemia prevalence levels, and for non-pregnant adult women, adolescent girls, and perimenopausal women living in areas with a high prevalence of anemia. Experts unanimously agreed to prescribing oral ferrous iron as first-line therapy for uncomplicated ID/IDA. The recommendations and clinical pathway algorithms generated should be used to inform clinical practice and standardize the care of women at risk or presenting with ID/IDA in the Asia-Pacific region.
KW - consensus
KW - Delphi
KW - iron deficiency
KW - iron deficiency anemia
KW - women
UR - http://www.scopus.com/inward/record.url?scp=85165980773&partnerID=8YFLogxK
U2 - 10.3390/nu15143125
DO - 10.3390/nu15143125
M3 - Article
C2 - 37513543
AN - SCOPUS:85165980773
SN - 2072-6643
VL - 15
JO - Nutrients
JF - Nutrients
IS - 14
M1 - 3125
ER -