Abstract
Objective: The aim of this study was to prepare powder from liquid extract with maltodextrin dextrose equivalent 10-15 as a stabilizer using a freezedrying method to maintain stability during drying process and extend storage time. Methods: Powders were prepared for four formulas: F1 (without maltodextrin), F2 (2.5% maltodextrin), F3 (5% maltodextrin), and F4 (10% maltodextrin). Powder from the four formulas was characterized by its phlorotannin concentration, antioxidant activity, water content, morphology, particle size distribution, pH, and organoleptic activities. Results: F4 was the best formula because it contained the highest phlorotannin concentration (113.06±1.36) or 0.25%, highest percentage of inhibition concentration50 (IC50) (4.06% at a concentration of 5000 ppm), and lowest water content (5.16%); moreover, in a stability test, F4 exhibited a more stable phlorotannin concentration and lower water content than F1, with an optimal storage temperature of 4°C. Conclusion: Maltodextrin can improve the stability bioactive compounds during the freeze-drying process and storage time.
| Original language | English |
|---|---|
| Pages (from-to) | 348-353 |
| Number of pages | 6 |
| Journal | International Journal of Applied Pharmaceutics |
| Volume | 10 |
| Issue number | Special Issue 1 |
| DOIs | |
| Publication status | Published - 1 Dec 2018 |
Keywords
- Freeze-drying
- Maltodextrin dextrose equivalent 10-15
- Phlorotannin
- Sargassum plagyophyllum
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