Premature Rupture of Membrane Outcome Determinants in Reproductive Age Women

Background:Premature Rupture of Membrane (PROM) may cause maternal and neonatal mor-bidity and mortality. This study aimed to investi-gate the risk factors related to PROM in pregnant women below <35 years old. Subjects and Method:This cross-sectional study was conducted in KerthaUsada General Hospital, North Bali, Indonesia.We collected 224 repoductive women usingconsecutive sampling.The dependent variable was prematurerupture of membrane. Theindependent variableswere gra-vidity status, gestational age, body mass index (BMI), history of caesarean section, miscarriage, infection,and anemia. Data of infectionwas obtained from examination, such as neutrophil, lymphocyte, platelet, neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR). We also obtained Hb, MCV, and MCH as laboratory parameter of anemia.The data were analyzed by a multiple logistic regression. Results: Multigravida(OR= 0.04; 95% CI= 0.01 to 0.27; p= 0.001) and MCH>34 pg (OR= 0.10; 95% CI= 0.01 to 0.86; p= 0.036) decreased the risk of premature of rupture membrane in women of reproductive age. Conclusion: Multigravidaand MCH>34 pg decrease the risk of premature of rupture mem-brane in women of reproductive age.