Potential of Malang Robusta Coffee Beans as Anti-breast Cancer In-Vitro

Novi Fajar Utami; Berna Elya; Hayun Hayun; Kusmardi Kusmardi; Syamsu Nur; Annisa Fajriati

doi:10.33751/jf.v13i2.8922

Potential of Malang Robusta Coffee Beans as Anti-breast Cancer In-Vitro

Novi Fajar Utami, Berna Elya, Hayun Hayun, Kusmardi Kusmardi, Syamsu Nur, Annisa Fajriati

Research output: Contribution to journal › Article › peer-review

Abstract

Robusta coffee from Malang Regency, East Java is one of the superior products of the largest coffee-producing region in Indonesia. The coffee has high antioxidants. The component that acts as an antioxidant is the tannin content, and these tannins are also anti-cancer. Using the UV-Vis spectrophotometry method the tannin content in Malang Robusta coffee beans is known and then to measure its ability as an anticancer in-vitro against breast cancer cells using MCF-7. The results showed that the tannin contained in Malang Robusta coffee bean extract was 2.81 % and inhibited MCF-7 at 400 µg/mL, it has potential as an anticancer with an inhibition value of 68.88 %. Therefore, the use of Robusta coffee from Malang at this concentration can be used as an anti-breast cancer agent.

Original language	English
Pages (from-to)	105-114
Journal	FITOFARMAKA: Jurnal Ilmiah Farmasi
Volume	13
Issue number	2
DOIs	https://doi.org/10.33751/jf.v13i2.8922
Publication status	Published - 29 Dec 2023

Keywords

Robusta
anticancer
MCF-7
in-vitro

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.33751/jf.v13i2.8922

Cite this

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title = "Potential of Malang Robusta Coffee Beans as Anti-breast Cancer In-Vitro",

abstract = "Robusta coffee from Malang Regency, East Java is one of the superior products of the largest coffee-producing region in Indonesia. The coffee has high antioxidants. The component that acts as an antioxidant is the tannin content, and these tannins are also anti-cancer. Using the UV-Vis spectrophotometry method the tannin content in Malang Robusta coffee beans is known and then to measure its ability as an anticancer in-vitro against breast cancer cells using MCF-7. The results showed that the tannin contained in Malang Robusta coffee bean extract was 2.81 % and inhibited MCF-7 at 400 µg/mL, it has potential as an anticancer with an inhibition value of 68.88 %. Therefore, the use of Robusta coffee from Malang at this concentration can be used as an anti-breast cancer agent.",

keywords = "Robusta, anticancer, MCF-7, in-vitro",

author = "Utami, {Novi Fajar} and Berna Elya and Hayun Hayun and Kusmardi Kusmardi and Syamsu Nur and Annisa Fajriati",

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doi = "10.33751/jf.v13i2.8922",

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T1 - Potential of Malang Robusta Coffee Beans as Anti-breast Cancer In-Vitro

AU - Utami, Novi Fajar

AU - Elya, Berna

AU - Hayun, Hayun

AU - Kusmardi, Kusmardi

AU - Nur, Syamsu

AU - Fajriati, Annisa

PY - 2023/12/29

Y1 - 2023/12/29

N2 - Robusta coffee from Malang Regency, East Java is one of the superior products of the largest coffee-producing region in Indonesia. The coffee has high antioxidants. The component that acts as an antioxidant is the tannin content, and these tannins are also anti-cancer. Using the UV-Vis spectrophotometry method the tannin content in Malang Robusta coffee beans is known and then to measure its ability as an anticancer in-vitro against breast cancer cells using MCF-7. The results showed that the tannin contained in Malang Robusta coffee bean extract was 2.81 % and inhibited MCF-7 at 400 µg/mL, it has potential as an anticancer with an inhibition value of 68.88 %. Therefore, the use of Robusta coffee from Malang at this concentration can be used as an anti-breast cancer agent.

AB - Robusta coffee from Malang Regency, East Java is one of the superior products of the largest coffee-producing region in Indonesia. The coffee has high antioxidants. The component that acts as an antioxidant is the tannin content, and these tannins are also anti-cancer. Using the UV-Vis spectrophotometry method the tannin content in Malang Robusta coffee beans is known and then to measure its ability as an anticancer in-vitro against breast cancer cells using MCF-7. The results showed that the tannin contained in Malang Robusta coffee bean extract was 2.81 % and inhibited MCF-7 at 400 µg/mL, it has potential as an anticancer with an inhibition value of 68.88 %. Therefore, the use of Robusta coffee from Malang at this concentration can be used as an anti-breast cancer agent.

KW - Robusta

KW - anticancer

KW - MCF-7

KW - in-vitro

UR - https://journal.unpak.ac.id/index.php/fitofarmaka/article/view/FJIF.v13i2.8922

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JF - FITOFARMAKA: Jurnal Ilmiah Farmasi

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ER -

Potential of Malang Robusta Coffee Beans as Anti-breast Cancer In-Vitro

Abstract

Keywords

UN SDGs

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