Allergy is a type I hypersensitivity reaction, which occurs when the body produces an excess of IgE antibody as a response to allergens. The development and severity of allergic diseases depend on a complex interaction between genetic and environmental factors. Pollen are one of the main environmental allergens. The allergenic pollens of the atmosphere varies according to climate, geography and vegetation. This research is conducted to study the pollen sensitivity reaction commonly occured among respiratory allergic (bronchial asthma and allergic rhinitis) patients in Jakarta. Total protein pollens of palm trees, coconut, pine, acacia, grass, maize, and rice were analyzed in denatured-state by SDS-PAGE and are dominated by proteins with molecular weight of 10-70 kD. Skin prick test with allergen protein of pollen were tested to sixty nine subjects whom have been diagnosed with respiratory allergic and sixty nine subjects without history of allergy. The results among respiratory allergic patients, showed that pollen from grass and acacia demonstrated a higher percentage of sensitivity response compared with other pollen.
|Journal||Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia|
|Publication status||Published - 2008|