TY - JOUR
T1 - PLA-Sago Starch Implants
T2 - The Optimization of Injection Molding Parameter and Plasticizer Material Compositions
AU - Whulanza, Yudan
AU - Taufiqurrakhman, Mohamad
AU - Supriadi, Sugeng
AU - Chalid, Mochamad
AU - Kreshanti, Prasetyanugraheni
AU - Azadi, Athoillah
N1 - Publisher Copyright:
© 2024 by the authors.
PY - 2024/3
Y1 - 2024/3
N2 - Previous research extensively characterized PLA blends for various biomedical applications, especially in polymer-based biodegradable implant fixations, offering advantages over metallic counterparts. Nevertheless, achieving an optimal PLA mixture with both mechanical resistance and fast biodegradability remains a challenge. Currently, literature still lacks insights into the manufacturing parameter impact on sago starch/PLA in combination with PEG plasticizer. The objective of this study is to assess variations in injection molding temperatures and sago/PLA/PEG weight compositions to identify the optimal combination enhancing miniplate mechanical properties and biodegradation behavior. Mechanical tests reveal that incorporating PEG into pure PLA yields high mechanical performance, correlating linearly with increasing injection temperature. However, the interaction once the three materials are mixed decreases mechanical performance across tested temperatures. Higher biodegradation rates are observed with a larger weight composition of the hydrophilic behavior attributed to sago starch presence. The observed novelty in PLA mixed with 20% sago starch and 10% PEG at 170 °C indicates a better performance in elastic modulus and elongation at break also the degradation rate, emphasizing the role of injection temperature in molding miniplate implants. In conclusion, the interplay of injection molding parameters and material compositions is crucial for optimizing PLA-based miniplate implants, with potential contributions to tissue implants rather than bone implants due to their mechanical limitation.
AB - Previous research extensively characterized PLA blends for various biomedical applications, especially in polymer-based biodegradable implant fixations, offering advantages over metallic counterparts. Nevertheless, achieving an optimal PLA mixture with both mechanical resistance and fast biodegradability remains a challenge. Currently, literature still lacks insights into the manufacturing parameter impact on sago starch/PLA in combination with PEG plasticizer. The objective of this study is to assess variations in injection molding temperatures and sago/PLA/PEG weight compositions to identify the optimal combination enhancing miniplate mechanical properties and biodegradation behavior. Mechanical tests reveal that incorporating PEG into pure PLA yields high mechanical performance, correlating linearly with increasing injection temperature. However, the interaction once the three materials are mixed decreases mechanical performance across tested temperatures. Higher biodegradation rates are observed with a larger weight composition of the hydrophilic behavior attributed to sago starch presence. The observed novelty in PLA mixed with 20% sago starch and 10% PEG at 170 °C indicates a better performance in elastic modulus and elongation at break also the degradation rate, emphasizing the role of injection temperature in molding miniplate implants. In conclusion, the interplay of injection molding parameters and material compositions is crucial for optimizing PLA-based miniplate implants, with potential contributions to tissue implants rather than bone implants due to their mechanical limitation.
KW - degradable implant
KW - degradable PLA
KW - PEG plasticizer
KW - sago starch
UR - http://www.scopus.com/inward/record.url?scp=85192436013&partnerID=8YFLogxK
U2 - 10.3390/app14051683
DO - 10.3390/app14051683
M3 - Article
AN - SCOPUS:85192436013
SN - 2076-3417
VL - 14
JO - Applied Sciences (Switzerland)
JF - Applied Sciences (Switzerland)
IS - 5
M1 - 1683
ER -