TY - JOUR
T1 - Physio-cognitive decline syndrome among middle-aged diabetes patients
T2 - Handgrip strength significantly correlates with glycaemic control and cognitive score
AU - Laksmi, Purwita Wijaya
AU - Purnamasari, Dyah
AU - Sofian, Naldo
AU - Sari, Nina Kemala
AU - Kurniawan, Mohammad
AU - Sukrisman, Lugyanti
AU - Tahapary, Dicky Levenus
AU - Dwimartutie, Noto
AU - Rinaldi, Ikhwan
N1 - Publisher Copyright:
© 2024 The Authors
PY - 2024/1/30
Y1 - 2024/1/30
N2 - Aims: To investigate the correlation between glycaemic control with component of Physio-Cognitive Decline Syndrome (PCDS) and among each component of PCDS itself. Methods: A cross sectional study was conducted (January 2021–November 2022) at Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia on consecutively recruited T2DM outpatients aged 40–59 years old. Data on the latest three months HbA1c, hand grip strength (HGS), usual gait speed (GS), and Indonesian Montreal Cognitive Assessment (MoCA-Ina) were evaluated. Pearson or Spearman's test was used to analyse the correlations. Results: There were 133 subjects with median age 53 (40–59) years. The PCDS was found in 48.1 % subjects, of which 64.1 % with uncontrolled glycaemia. Significant correlations were found between HGS and HbA1c (r = −0.24, R2 = 0.06, p < 0.01) and MoCA-Ina score (r = 0.21, R2 = 0.04, p < 0.05). Conclusion: The higher HbA1c and the lower MoCA-Ina score, the weaker handgrip strength was.
AB - Aims: To investigate the correlation between glycaemic control with component of Physio-Cognitive Decline Syndrome (PCDS) and among each component of PCDS itself. Methods: A cross sectional study was conducted (January 2021–November 2022) at Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia on consecutively recruited T2DM outpatients aged 40–59 years old. Data on the latest three months HbA1c, hand grip strength (HGS), usual gait speed (GS), and Indonesian Montreal Cognitive Assessment (MoCA-Ina) were evaluated. Pearson or Spearman's test was used to analyse the correlations. Results: There were 133 subjects with median age 53 (40–59) years. The PCDS was found in 48.1 % subjects, of which 64.1 % with uncontrolled glycaemia. Significant correlations were found between HGS and HbA1c (r = −0.24, R2 = 0.06, p < 0.01) and MoCA-Ina score (r = 0.21, R2 = 0.04, p < 0.05). Conclusion: The higher HbA1c and the lower MoCA-Ina score, the weaker handgrip strength was.
KW - Diabetes mellitus
KW - Gait speed
KW - Hand grip strength
KW - MoCA
KW - Physio-cognitive decline syndrome
UR - http://www.scopus.com/inward/record.url?scp=85182358528&partnerID=8YFLogxK
U2 - 10.1016/j.heliyon.2024.e24018
DO - 10.1016/j.heliyon.2024.e24018
M3 - Article
AN - SCOPUS:85182358528
SN - 2405-8440
VL - 10
JO - Heliyon
JF - Heliyon
IS - 2
M1 - e24018
ER -
