TY - JOUR
T1 - Pharmacognostical and phytochemical evaluation leaves extract of garcinia daedalanthera pierre
AU - Najib, Sarah Zielda
AU - Ekayanti, Meiliza
AU - Ardiana, Lia
AU - Sauriasari, Rani
AU - Elya, Berna
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Background: Garcinia daedalanthera is an Indonesian plant where commonly found in Sulawesi, Indonesia and spread out in the forest. Garcinia daedalanthera is one of Clusiaceae family that have been scientifically proven to provideanti diabetic and antioxidant activity but never been examined in pharmacognosy parameters. Pharmacognostical parameters of the leaves were studied with the aim of drawing the pharmacopoeial standards for this species. Methods: The present study was aimed to analysis the pharmacognosy of Garcinia daedalanthera including leaf morphology, microscopic characteristics, physicochemical parameters, phytochemical study, contaminant analysis and FTIR spectrum analysis. Results: The phytochemical analysis revealed the presence of flavonoids, saponins, tannin, steroids and phenols. The moisture content was 2.35%, total ash 2.51%, acid insoluble ash 0.05%, total flavonoid and phenolic content were found to be 3.121% and 14.36% (w/w). The level of Arsenic (As), Cadmium (Cd) and lead (Pb) were found under the limit (0.357 ppm) and the extract of leaves Garcinia daedalanthera Pierre does not contain bacterial contamination. Conclusion: The data generated from this study would help in standardization for pharmacopoeial and prevent adulteration of leaves extract of Garcinia daedalanthera Pierre and the authentic plant material can be explored for its pharmacological.
AB - Background: Garcinia daedalanthera is an Indonesian plant where commonly found in Sulawesi, Indonesia and spread out in the forest. Garcinia daedalanthera is one of Clusiaceae family that have been scientifically proven to provideanti diabetic and antioxidant activity but never been examined in pharmacognosy parameters. Pharmacognostical parameters of the leaves were studied with the aim of drawing the pharmacopoeial standards for this species. Methods: The present study was aimed to analysis the pharmacognosy of Garcinia daedalanthera including leaf morphology, microscopic characteristics, physicochemical parameters, phytochemical study, contaminant analysis and FTIR spectrum analysis. Results: The phytochemical analysis revealed the presence of flavonoids, saponins, tannin, steroids and phenols. The moisture content was 2.35%, total ash 2.51%, acid insoluble ash 0.05%, total flavonoid and phenolic content were found to be 3.121% and 14.36% (w/w). The level of Arsenic (As), Cadmium (Cd) and lead (Pb) were found under the limit (0.357 ppm) and the extract of leaves Garcinia daedalanthera Pierre does not contain bacterial contamination. Conclusion: The data generated from this study would help in standardization for pharmacopoeial and prevent adulteration of leaves extract of Garcinia daedalanthera Pierre and the authentic plant material can be explored for its pharmacological.
KW - FTIR
KW - Garcinia daedalanthera extract
KW - Macromicroscopy study
KW - Pharmacognosy study
KW - Preliminary screening
KW - Standardization
UR - http://www.scopus.com/inward/record.url?scp=85016962119&partnerID=8YFLogxK
U2 - 10.5530/jyp.2017.1s.16
DO - 10.5530/jyp.2017.1s.16
M3 - Article
AN - SCOPUS:85016962119
SN - 0975-1483
VL - 9
SP - S60-S64
JO - Journal of Young Pharmacists
JF - Journal of Young Pharmacists
IS - 1
ER -