Phantom design for quality control of Positron Emission Tomography/Computed Tomography (PET/CT) imaging

I. A.S. Mu'Minah, Ratianto, Nurlely, D. S. Soejoko

Research output: Contribution to journalConference articlepeer-review

Abstract

This research was aimed to develop an in-house phantom for quality control (QC) of image quality in PET/CT imaging. Wax and rice powder were mixed to produce tissue-equivalent materials characterized by Hounsfield Unit (HU). The in-house phantom was two circular cylinders with 20 cm in diameter and 10 cm in length which consists of six symmetric vessel pairs with varied diameters of 4.20, 6.20, 8.30, 9.80, 16.30, and 19.00 mm. Each measurement was performed using radioactivity concentrations of 18F-FDG with variation from 1 to 17Ci/mL Images were displayed with the pixel size of 4 × 4 mm2. Image quality was evaluated in terms of conversion factor between full-width-half-maximum (FWHM) and actual diameter, and a pixel value for local uniformity of each object. Two types of phantoms have been designed which were liver-equivalent material (LEM) and muscle-equivalent material (MEM). HU and electron densities were (74.17 ± 1.48) HU and 3.396 × 1023 electron/m3 for LEM, while (20.27 ± 0.33) HU and 3.461 × 1023 electron/m3 for MEM, respectively. The conversion factor was initially high at 2.240 ± 0.07 for diameter 4.20 mm, falls to 0.99 ± 0.003 for diameter 9.80 mm, slowly decrease up to 0.82 ± 0.01 at diameter 16.30 mm, and then nearly constant at 0.82 with increasing diameter for both phantoms. The in-house phantom could be used to analyse the image quality performance of PET imaging with a tissue-specific material. The phantom design including the development of tissue-surrogate materials, size, and geometrical considerations of the features will be beneficial for innovating QC tools.

Original languageEnglish
Article number012031
JournalJournal of Physics: Conference Series
Volume1248
Issue number1
DOIs
Publication statusPublished - 6 Jun 2019
Event18th Asia-Oceania Congress of Medical Physics, AOCMP 2018 and 16th South-East Asia Congress of Medical Physics, SEACOMP 2018 - Bangsar South, Kuala Lumpur, Malaysia
Duration: 11 Nov 201814 Nov 2018

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