Currently, the most of implant products that sold in Indonesia are imported products. The Ministry of Health and the Ministry of Research, Technology and Higher Education stimulate domestic implant production as an alternative for imported products that have been dominating domestic market. This study aims to observe domestic titanium screw performance especially from torque and pullout performance based on ASTM F-532 about test method for a metallic bone screw. The implant specification that observed is screw M1.5 for maxillofacial region. Those performances are tested using experimental approach, Finite Element Analysis (FEA), and mathematical approach for pullout and only experimental approach for torque test. The results of this study show that the value of pullout from the developed domestic titanium screw UI and commercial screw are 10.02 N and 11.88 N, respectively. This result for domestic screw UI is not slightly different from the result which using FEA approach with error 10.30 % for pullout. In the other hands, analytical approach using Chapman modified method gives 1% error for pullout. The result of this study shows that the value of pullout performance of domestic titanium screw is equal with imported commercial product. For torque performance, domestic screw UI has value 0.029 Nm which is as good as commercial screw with value 0.028 Nm. But, domestic screw needs more force to drive the screw into the test block because it has duller tip than commercial screw.