TY - GEN
T1 - Performance evaluation of a 3D structured phantom with simulated lesions on breast imaging systems
AU - Vancoillie, Liesbeth
AU - Cockmartin, Lesley
AU - Wigati, Kristina Tri
AU - Petrov, Dimitar
AU - Zhang, Guozhi
AU - Marshall, Nicholas
AU - Bosmans, Hilde
N1 - Publisher Copyright:
© 2018 SPIE.
PY - 2018
Y1 - 2018
N2 - The purpose of this study is comparing the detection performance in 2D full field digital mammography (FFDM) and digital breast tomosynthesis (DBT) using a structured phantom with inserted target objects. The phantom consists of a semi-cylindrical PMMA container, filled with water and PMMA spheres of different diameters. Microcalcifications and 3D printed masses (spiculated and non-spiculated) were inserted. The phantom was imaged ten times in both modes of five systems, using automatic exposure control (AEC) and at half and double the AEC dose. Five readers evaluated target detectability in a four-alternative forced-choice study. The percentage of correct responses (PC) was assessed based on 10 trials of each reader for each object type, size, imaging modality and dose level. Additionally, detection threshold diameters at 62.5 PC were assessed via non-linear regression fitting of the psychometric curve. Evaluation of target detection in FFDM showed that spiculated masses were better detected compared to non-spiculated masses. In DBT, detection of both mass types increased significantly (p=0.0001) compared to FFDM. Microcalcification detection thresholds ranged between 110 and 118 μm and were similar for the five systems in FFDM while larger variations (106-158 μm) were found in DBT. Mass detection was independent of dose in FFDM while weak dependence was seen for DBT. Microcalcification detection increased with increasing dose for both modalities. The phantom was able to show detectability differences between FFDM and DBT mode for five commercial systems in line with the findings from clinical trials. We suggest to use the phantom for task-based assessment methods for acceptance and commissioning testing of DBT systems.
AB - The purpose of this study is comparing the detection performance in 2D full field digital mammography (FFDM) and digital breast tomosynthesis (DBT) using a structured phantom with inserted target objects. The phantom consists of a semi-cylindrical PMMA container, filled with water and PMMA spheres of different diameters. Microcalcifications and 3D printed masses (spiculated and non-spiculated) were inserted. The phantom was imaged ten times in both modes of five systems, using automatic exposure control (AEC) and at half and double the AEC dose. Five readers evaluated target detectability in a four-alternative forced-choice study. The percentage of correct responses (PC) was assessed based on 10 trials of each reader for each object type, size, imaging modality and dose level. Additionally, detection threshold diameters at 62.5 PC were assessed via non-linear regression fitting of the psychometric curve. Evaluation of target detection in FFDM showed that spiculated masses were better detected compared to non-spiculated masses. In DBT, detection of both mass types increased significantly (p=0.0001) compared to FFDM. Microcalcification detection thresholds ranged between 110 and 118 μm and were similar for the five systems in FFDM while larger variations (106-158 μm) were found in DBT. Mass detection was independent of dose in FFDM while weak dependence was seen for DBT. Microcalcification detection increased with increasing dose for both modalities. The phantom was able to show detectability differences between FFDM and DBT mode for five commercial systems in line with the findings from clinical trials. We suggest to use the phantom for task-based assessment methods for acceptance and commissioning testing of DBT systems.
KW - detection performance
KW - digital breast tomosynthesis
KW - digital mammography
KW - four alternative forced choice study
KW - structured phantom
UR - http://www.scopus.com/inward/record.url?scp=85050250426&partnerID=8YFLogxK
U2 - 10.1117/12.2318472
DO - 10.1117/12.2318472
M3 - Conference contribution
AN - SCOPUS:85050250426
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - 14th International Workshop on Breast Imaging (IWBI 2018)
A2 - Krupinski, Elizabeth A.
PB - SPIE
T2 - 14th International Workshop on Breast Imaging (IWBI 2018)
Y2 - 8 July 2018 through 11 July 2018
ER -