PERBANDINGAN UJI DIAGNOSTIK MINI FLOTAC DENGAN KATO-KATZ SEBELUM DAN SESUDAH PENGOBATAN ALBENDAZOL DOSIS TUNGGAL PADA ANAK YANG TERINFEKSI CACING USUS

To monitor anthelmintic treatment, will require examination techniques that are more accurate and sensitive than the Kato-Katz technique which is the current standard. This study is a diagnostic examination performed on primary school children. It was conducted in March 2013 in Kalibaru village, Cilincing Sub-District, North Jakarta. Stool samples were examined using the KatoKatz and Mini FLOTAC methods on day 7,14, and 21 after the administration of a single dose of 400 mg albendazole. Of the 209 study subjects, 197 subjects were willing to participate. Before treatment, the sensitivity and the NPV (negative predictive value) against A. lumbricoides infection were 94%,96%, respectively for Kato-Katz and 81%, 88%, respectively for Mini FLOTAC. For T. trichiura, sensitivity and the NPV of Kato-Katz were 88%, 92%, respectively,while for Mini FLOTAC both values were 100%. Kappa value of agreement between Kato-Katz and Mini FLOTAC techniques was 0.773 for the diagnosis of A. lumbricoides infection and 0.895 for T. trichiura. For Ascaris, 19.79% versus 25.88% of infected children have light infection by Kato-Katz and Mini FLOTAC, respectively. For Trichuris, 34.51% versus 42.13% of infected children have light infection with KatoKatz and Mini FLOTAC, respectively. After the treatment was given, Kato-Katz was more sensitive compared to Mini FLOTAC in detecting A. lumbricoides infection, especially at day 7 and day 14. On the contrary, Mini FLOTAC was more sensitive in detecting T. trichiura infection. The Mini FLOTAC
technique can be used as an alternative for Kato-Katz in detecting helminth infections. Mini FLOTAC was more sensitive to detect T. trichiura compared to Kato-Katz.