TY - JOUR
T1 - Peran prostaglandin pada pergerakan gigi ortodontik
AU - Iskandar, Patricia
AU - Suria, Nia Ayu Ismaniati
PY - 2010
Y1 - 2010
N2 - Orthodontic tooth movement is a complex process, in which cellular and chemical changes occur. When a force is applied onto a tooth, it causes tissue injury, compression of periodontal ligament and bone deformation. These procedures lead to followed by certain biochemical reactions at cellular level which results in bone remodeling. Thus a process of signal transduction occurs. In this process, some messengers are released, including prostaglandin. Prostaglandin is an arachidonic acid metabolite, released when cell membrane is deformed. Prostaglandin, particularly PGE, play a role in bone metabolism and orthodontic tooth movement. Prostaglandin will stimulate the release of second messengers, i.e. cAMP and calcium intracellular. These second messengers will activate osteoclasts. Prostaglandin will also induce RANKL (receptor activator of nuclear factor κβ ligand) to initiate osteoclasts differentiation. Some researchers proved that application of prostaglandin in orthodontic treatment can accelerate tooth movement.
AB - Orthodontic tooth movement is a complex process, in which cellular and chemical changes occur. When a force is applied onto a tooth, it causes tissue injury, compression of periodontal ligament and bone deformation. These procedures lead to followed by certain biochemical reactions at cellular level which results in bone remodeling. Thus a process of signal transduction occurs. In this process, some messengers are released, including prostaglandin. Prostaglandin is an arachidonic acid metabolite, released when cell membrane is deformed. Prostaglandin, particularly PGE, play a role in bone metabolism and orthodontic tooth movement. Prostaglandin will stimulate the release of second messengers, i.e. cAMP and calcium intracellular. These second messengers will activate osteoclasts. Prostaglandin will also induce RANKL (receptor activator of nuclear factor κβ ligand) to initiate osteoclasts differentiation. Some researchers proved that application of prostaglandin in orthodontic treatment can accelerate tooth movement.
UR - https://jdmfs.org/index.php/jdmfs/article/view/238
M3 - Article
SN - 2503-0825
JO - Journal of Dentomaxillofacial Science
JF - Journal of Dentomaxillofacial Science
ER -