PDMS surface modification using biomachining method for biomedical application

Yudan Whulanza; Hanif Nadhif; Jos Istiyanto; Sugeng Supriadi; B. M. Bachtiar

doi:10.4028/www.scientific.net/JBBBE.26.66

PDMS surface modification using biomachining method for biomedical application

Yudan Whulanza, Hanif Nadhif, Jos Istiyanto, Sugeng Supriadi, B. M. Bachtiar

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

Engineering a cell-friendly material in a form of lab-on-chip is the main goal of this study. The chip was made of polydimethyl siloxane (PDMS) with a surface modification to realize a groovy structure on its surface. This groovy surface was naturally and randomly designed using biomachining process. This measure was aimed to improve the cell attachment on the PDMS surface that always known as hydrophobic surface. The biomachined surface of mold and also products were characterized as surface roughness and wettability. The result shows that the biomachining process were able to be characterized in three classes of roughness on the surface of PDMS.

Original language	English
Pages (from-to)	66-72
Number of pages	7
Journal	Journal of Biomimetics, Biomaterials and Biomedical Engineering
Volume	26
DOIs	https://doi.org/10.4028/www.scientific.net/JBBBE.26.66
Publication status	Published - 2016

Keywords

Biomachining
Groovy surface
Lab-on-Chip
PDMS modification

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abstract = "Engineering a cell-friendly material in a form of lab-on-chip is the main goal of this study. The chip was made of polydimethyl siloxane (PDMS) with a surface modification to realize a groovy structure on its surface. This groovy surface was naturally and randomly designed using biomachining process. This measure was aimed to improve the cell attachment on the PDMS surface that always known as hydrophobic surface. The biomachined surface of mold and also products were characterized as surface roughness and wettability. The result shows that the biomachining process were able to be characterized in three classes of roughness on the surface of PDMS.",

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AU - Whulanza, Yudan

AU - Nadhif, Hanif

AU - Istiyanto, Jos

AU - Supriadi, Sugeng

AU - Bachtiar, B. M.

PY - 2016

Y1 - 2016

N2 - Engineering a cell-friendly material in a form of lab-on-chip is the main goal of this study. The chip was made of polydimethyl siloxane (PDMS) with a surface modification to realize a groovy structure on its surface. This groovy surface was naturally and randomly designed using biomachining process. This measure was aimed to improve the cell attachment on the PDMS surface that always known as hydrophobic surface. The biomachined surface of mold and also products were characterized as surface roughness and wettability. The result shows that the biomachining process were able to be characterized in three classes of roughness on the surface of PDMS.

AB - Engineering a cell-friendly material in a form of lab-on-chip is the main goal of this study. The chip was made of polydimethyl siloxane (PDMS) with a surface modification to realize a groovy structure on its surface. This groovy surface was naturally and randomly designed using biomachining process. This measure was aimed to improve the cell attachment on the PDMS surface that always known as hydrophobic surface. The biomachined surface of mold and also products were characterized as surface roughness and wettability. The result shows that the biomachining process were able to be characterized in three classes of roughness on the surface of PDMS.

KW - Biomachining

KW - Groovy surface

KW - Lab-on-Chip

KW - PDMS modification

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JO - Journal of Biomimetics, Biomaterials and Biomedical Engineering

JF - Journal of Biomimetics, Biomaterials and Biomedical Engineering

ER -

PDMS surface modification using biomachining method for biomedical application

Abstract

Keywords

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