TY - JOUR
T1 - Patterns of menstrual cycle, menstrual pain and medication usage in young women from high- and middle-income countries
AU - Endometriosis Awareness Promotion Project (EAPP) Collaboration Group
AU - Khan, Khaleque N.
AU - Ogawa, Kanae
AU - Iwasa, Koichi
AU - Kuroboshi, Haruo
AU - Koshiba, Akemi
AU - Okimura, Hiroyuki
AU - Kitawaki, Jo
AU - Mori, Taisuke
AU - Matsuoka, Tomoko
AU - Teramukai, Satoshi
AU - Horiguchi, Go
AU - Itoh, Kyoko
AU - Sawa, Teiji
AU - Matoba, Satoaki
AU - Fushiki, Shinji
AU - Fujishita, Akira
AU - Nakashima, Masahiro
AU - Manabe, Emiko
AU - Izumi, Mie
AU - Nasu, Kaei
AU - Kai, Kentaro
AU - Aoyagi, Yoko
AU - Terauchi, Masakazu
AU - Iwahara, Yuki
AU - Aoki, Yoichi
AU - Mekaru, Keiko
AU - Harada, Tasuku
AU - Taniguchi, Fuminori
AU - Fukui, Atsushi
AU - Yamaya, Ayano
AU - Wakimoto, Yu
AU - Shibahara, Hiroaki
AU - Ramasauskaite, Diana
AU - Silkunas, Mindaugas
AU - Cerniauskaite, Migle
AU - Shaikenovna, Issenona Saule
AU - Bakytkhan, Kabyl
AU - Nurbolat, Zhambylov
AU - Guo, Sun Wei
AU - Senanayake, Hemantha
AU - Thi, Thu Ha Nguyen
AU - Tuan, Dat
AU - Anh, Nguyen Duy
AU - Le, Minh Tam
AU - Nguyen, Dac Nguyen
AU - Nguyen, Quoc Huy Vu
AU - Hestiantoro, Andon
AU - Kemal, Achmad
AU - Muharam, Raden
AU - Celik, Hale Goksever
N1 - Publisher Copyright:
© 2024 Reproductive Healthcare Ltd.
PY - 2024/8
Y1 - 2024/8
N2 - Research question: Do patterns of the menstrual cycle, menstrual pain and the use of medication for menstrual pain differ between young women from high-income countries (HIC) and middle-income countries (MIC)? Design: A multinational, multicentre, cross-sectional study using pen-and-paper questionnaires was conducted between 2016 and 2021 to assess patterns of the menstrual cycle, menstrual pain and the use of medication for menstrual pain. Various parameters were evaluated to identify high-risk factors for severe menstrual pain in women from two HIC (n = 1550) and nine MIC (n = 7139). Results: From a total of 9114 young women, 4920 medical students (HIC n = 696, MIC n = 4224) and 3769 nursing students (HIC n = 854, MIC n = 2915) were included in this study. Compared with those from HIC, a significantly higher proportion of medical and nursing students from MIC reported cyclic pain (83.9% and 86.8%, respectively) and acyclic pain (33.8% and 31.9%, respectively) (both P < 0.001). Multivariate regression analysis revealed that low body mass index and early onset of menarche were independent risk factors for severe cyclic/acyclic pain among women from HIC, and a family history of menstrual pain was a risk factor for severe cyclic/acyclic pain among women from HIC and MIC. Conclusions: Differential patterns of the menstrual cycle, menstrual pain and use of medication for menstrual pain were found between young women from HIC and MIC. A proper educational programme may be necessary for these women and healthcare providers to understand the consequences of intractable cyclic/acyclic pain, in order to facilitate early detection and timely management of menstrual pain and its negative consequences, such as endometriosis.
AB - Research question: Do patterns of the menstrual cycle, menstrual pain and the use of medication for menstrual pain differ between young women from high-income countries (HIC) and middle-income countries (MIC)? Design: A multinational, multicentre, cross-sectional study using pen-and-paper questionnaires was conducted between 2016 and 2021 to assess patterns of the menstrual cycle, menstrual pain and the use of medication for menstrual pain. Various parameters were evaluated to identify high-risk factors for severe menstrual pain in women from two HIC (n = 1550) and nine MIC (n = 7139). Results: From a total of 9114 young women, 4920 medical students (HIC n = 696, MIC n = 4224) and 3769 nursing students (HIC n = 854, MIC n = 2915) were included in this study. Compared with those from HIC, a significantly higher proportion of medical and nursing students from MIC reported cyclic pain (83.9% and 86.8%, respectively) and acyclic pain (33.8% and 31.9%, respectively) (both P < 0.001). Multivariate regression analysis revealed that low body mass index and early onset of menarche were independent risk factors for severe cyclic/acyclic pain among women from HIC, and a family history of menstrual pain was a risk factor for severe cyclic/acyclic pain among women from HIC and MIC. Conclusions: Differential patterns of the menstrual cycle, menstrual pain and use of medication for menstrual pain were found between young women from HIC and MIC. A proper educational programme may be necessary for these women and healthcare providers to understand the consequences of intractable cyclic/acyclic pain, in order to facilitate early detection and timely management of menstrual pain and its negative consequences, such as endometriosis.
KW - Endometriosis
KW - High-income countries
KW - Medication
KW - Menstrual pain
KW - Middle-income countries
KW - Young women
UR - http://www.scopus.com/inward/record.url?scp=85194577487&partnerID=8YFLogxK
U2 - 10.1016/j.rbmo.2024.103942
DO - 10.1016/j.rbmo.2024.103942
M3 - Article
C2 - 38823306
AN - SCOPUS:85194577487
SN - 1472-6483
VL - 49
JO - Reproductive BioMedicine Online
JF - Reproductive BioMedicine Online
IS - 2
M1 - 103942
ER -