TY - JOUR
T1 - Optimization of ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate ([Bmim] PF6)-based microwave assisted extraction method for gamma oryzanol from rice bran (Oryza Sativa L.)
AU - Trinovita, Elsa
AU - Sigalingging, Efendy
AU - Saputri, Fadlina Chany
AU - Mun'im, Abdul
N1 - Publisher Copyright:
© 2017 Elsa Trinovita et al.
PY - 2017/12
Y1 - 2017/12
N2 - The effect of IL solvent and the microwave-assisted extraction (MAE) including concentration IL, the ratio of liquid/solid, time extraction and microwave power in the result of gamma oryzanol extract in rice bran (Oryza Sativa L.) were investigated. The application of IL [Bmim] PF6 as a selected solvent in the MAE method was developed for the extraction of gamma oryzanol from rice bran. The Box-Behnken design on four factors with response surface methodology version 10 was used to optimize experimental conditions. The optimum process for the MAE using ionic liquids ([Bmim]PF6) concentration 0.7 M [Bmim]PF6 solution, the ratio of liquid/solid 15mL/g, extraction time 10 min, and 30% microwave power with the gamma oryzanol value of 0.27 mg/g.The IL-MAE method is more efficient for the extraction of gamma oryzanol compounds from rice bran.
AB - The effect of IL solvent and the microwave-assisted extraction (MAE) including concentration IL, the ratio of liquid/solid, time extraction and microwave power in the result of gamma oryzanol extract in rice bran (Oryza Sativa L.) were investigated. The application of IL [Bmim] PF6 as a selected solvent in the MAE method was developed for the extraction of gamma oryzanol from rice bran. The Box-Behnken design on four factors with response surface methodology version 10 was used to optimize experimental conditions. The optimum process for the MAE using ionic liquids ([Bmim]PF6) concentration 0.7 M [Bmim]PF6 solution, the ratio of liquid/solid 15mL/g, extraction time 10 min, and 30% microwave power with the gamma oryzanol value of 0.27 mg/g.The IL-MAE method is more efficient for the extraction of gamma oryzanol compounds from rice bran.
KW - Gamma oryzanol
KW - IL-MAE
KW - Ionic liquid
KW - Response surface methodology (RSM)
KW - [Bmim] PF
UR - http://www.scopus.com/inward/record.url?scp=85041954556&partnerID=8YFLogxK
U2 - 10.7324/JAPS.2017.71202
DO - 10.7324/JAPS.2017.71202
M3 - Article
AN - SCOPUS:85041954556
SN - 2231-3354
VL - 7
SP - 8
EP - 13
JO - Journal of Applied Pharmaceutical Science
JF - Journal of Applied Pharmaceutical Science
IS - 12
ER -